Optimal Designs for Non-Compartmental Analysis of Pharmacokinetic Studies

Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T. F., 2018, In: Statistics in Biopharmaceutical Research. 10, 4, p. 255-263 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Optimal dose and safety of molnupiravir in patients with early SARS-CoV-2: a Phase I, open-label, dose-escalating, randomized controlled study

Khoo, S. H., Fitzgerald, R., Fletcher, T., Ewings, S., Jaki, T., Lyon, R., Downs, N., Walker, L., Tansley-Hancock, O., Greenhalf, W., Woods, C., Reynolds, H., Marwood, E., Mozgunov, P., Adams, E., Bullock, K., Holman, W., Bula, M. D., Gibney, J. L., Saunders, G., & 18 othersCorkhill, A., Hale, C., Thorne, K., Chiong, J., Condie, S., Pertinez, H., Painter, W., Wrixon, E., Johnson, L., Yeats, S., Mallard, K., Radford, M., Fines, K., Shaw, V., Owen, A., Lalloo, D. G., Jacobs, M. & Griffiths, G., 12/11/2021, In: Journal of Antimicrobial Chemotherapy. 76, 12, p. 3286-3295 10 p.

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Optimization, refinement and reduction of murine in vivo experiments to assess therapeutic approaches for hemophilia A.

Baumgartner, B., Jaki, T., Wolfsegger, M. J., Eder, B., Schiviz, A., Schwarz, H. P. & Muchitsch, E. M., 07/2010, In: Laboratory Animals. 44, 3, p. 211-217 7 p.

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Optimizing subgroup selection in two-stage adaptive enrichment and umbrella designs

Ballarini, N. M., Burnett, T., Jaki, T., Jennison, C., König, F. & Posch, M., 31/05/2021, In: Statistics in Medicine. 40, 12, p. 2939-2956 18 p.

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Performance of different clinical trial designs to evaluate treatments during an epidemic

Brueckner, M., Titman, A. C., Jaki, T. F., Rojek, A. & Horby, P. W., 11/09/2018, In: PLoS ONE. 13, 9, 19 p., e0203387.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Planning multi-arm screening studies within the context of a drug development programme

Wason, J., Jaki, T. & Stallard, N., 10/09/2013, In: Statistics in Medicine. 32, 20, p. 3424-3435 12 p.

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Point estimation for adaptive trial designs I: A methodological review

Robertson, D. S., Choodari‐Oskooei, B., Dimairo, M., Flight, L., Pallmann, P. & Jaki, T., 30/01/2023, In: Statistics in Medicine. 42, 2, p. 122-145 24 p.

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Practical guidance for planning resources required to support publicly-funded adaptive clinical trials

Wason, J. M. S., Dimairo, M., Biggs, K., Bowden, S., Brown, J., Flight, L., Hall, J., Jaki, T., Lowe, R., Pallmann, P., Pilling, M. A., Snowdon, C., Sydes, M. R., Villar, S. S., Weir, C. J., Wilson, N., Yap, C., Hancock, H. & Maier, R., 10/08/2022, In: BMC Medicine. 20, 1, 12 p., 254.

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Practical implementation of the partial ordering continual reassessment method in a Phase I combination‐schedule dose‐finding trial

Mozgunov, P., Jaki, T., Gounaris, I., Goddemeier, T., Victor, A. & Grinberg, M., 30/12/2022, In: Stat. Med.. 41, 30, p. 5789-5809 21 p.

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Practical recommendations for implementing a Bayesian adaptive phase I design during a pandemic

Ewings, S., Saunders, G., Jaki, T. & Mozgunov, P., 20/01/2022, In: BMC Medical Research Methodology. 22, 1, 15 p., 25.

Research output: Contribution to Journal/Magazine › Journal article › peer-review