Designing multi-arm multi-stage clinical trials using a risk-benefit criterion for treatment selection

Jaki, T. & Hampson, L., 20/02/2016, In: Statistics in Medicine. 35, 4, p. 522-533 12 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Designing exploratory cancer trials using change in tumour size as primary endpoint

Jaki, T., Andre, V., Su, T-L. & Whitehead, J., 10/07/2013, In: Statistics in Medicine. 32, 15, p. 2544-2554 11 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Designing and evaluating dose-escalation studies made easy: The MoDEsT web app

Pallmann, P., Wan, F., Mander, A. P., Wheeler, G. M., Yap, C., Clive, S., Hampson, L. V. & Jaki, T., 1/04/2020, In: Clinical Trials. 17, 2, p. 147-156 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Design and estimation in clinical trials with subpopulation selection

Chiu, Y-D., Koenig, F., Posch, M. & Jaki, T. F., 20/12/2018, In: Statistics in Medicine. 37, 29, p. 4335-4352 18 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Creating a framework for conducting randomized clinical trials during disease outbreaks

Dean, N. E., Gsell, P-S., Brookmeyer, R., Crawford, F. W., Donnelly, C. A., Ellenberg, S. S., Fleming, T. R., Halloran, E. M., Horby, P., Jaki, T., Krause, P. R., Longini, I. M., Mulangu, S., Muyembe-Tamfum, J-J., Nason, M. C., Smith, P. G., Wang, R., Henao-Restrepo, A. M. & De Gruttola, V., 2/04/2020, In: New England Journal of Medicine. 382, 14, p. 1366-1369 4 p.

Research output: Contribution to Journal/Magazine › Editorial › peer-review

Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project

Wilson, N., Biggs, K., Bowden, S., Brown, J., Dimairo, M., Flight, L., Hall, J., Hockaday, A., Jaki, T., Lowe, R., Murphy, C., Pallmann, P., Pilling, M. A., Snowdon, C., Sydes, M. R., Villar, S. S., Weir, C. J., Welburn, J., Yap, C., Maier, R., & 2 othersHancock, H. & Wason, J. M. S., 26/10/2021, In: BMC Medicine. 19, 1, 17 p., 251.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Considerations on covariates and endpoints in multi-arm multi-stage clinical trials selecting all promising treatments

Jaki, T. & Magirr, D., 30/03/2013, In: Statistics in Medicine. 32, 7, p. 1150-1163 14 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Confidence regions for treatment effects in subgroups in biomarker stratified designs

Wan, F., Kunz, C. U. & Jaki, T. F., 1/01/2019, In: Biometrical Journal. 61, 1, p. 27-39 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Confidence Intervals for Ratios of AUC's in the Case of Serial Sampling : A Comparison of Seven Methods.

Jaki, T., Wolfsegger, M. J. & Ploner, M., 01/2009, In: Pharmaceutical Statistics. 8, 1, p. 12-24 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Comparing sampling methods for pharmacokinetic studies using model averaged derived parameters

Barnett, H. Y., Geys, H., Jacobs, T. & Jaki, T., 30/11/2017, In: Statistics in Medicine. 36, 27, p. 4301-4315 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Clinical drug development in epilepsy revisited: a proposal for a new paradigm streamlined using extrapolation

Wadsworth, I., Jaki, T. F., Sills, G. J., Appleton, R., Cross, J. H., Marson, A. G., Martland, T., McLellan, A., Smith, P. E. M., Pellock, J. M. & Hampson, L. V., 11/2016, In: CNS Drugs. 30, 11, p. 1011-1017 7 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bridging across patient subgroups in phase I oncology trials that incorporate animal data

Zheng, H., Hampson, L. V. & Jaki, T., 1/04/2021, In: Statistical Methods in Medical Research. 30, 4, p. 1057-1071 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Book review: Applied Nonparametric Statistical Methods.

Jaki, T., 2008, In: Journal of Biopharmaceutical Statistics. 18, 2, p. 393-395 3 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Book review : Bioequivalence and statistics in clinical pharmacology.

Jaki, T., 04/2010, In: Journal of the Royal Statistical Society: Series A Statistics in Society. 173, 2, p. 467-468 2 p.

Research output: Contribution to Journal/Magazine › Book/Film/Article review

Bayesian sequential integration within a preclinical pharmacokinetic and pharmacodynamic modeling framework: Lessons learned

La Gamba, F., Jacobs, T., Geys, H., Jaki, T., Serroyen, J., Ursino, M., Russu, A. & Faes, C., 1/07/2019, In: Pharmaceutical Statistics. 18, 4, p. 486-506 21 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bayesian sample size determination using commensurate priors to leverage pre‐experimental data

Zheng, H., Jaki, T. & Wason, J. M. S., 30/06/2023, In: Biometrics. 79, 2, p. 669-683 15 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Bayesian adaptive dose-escalation procedures for binary and continuous responses utilizing a gain function

Yeung, W. Y., Whitehead, J. R., Reigner, B., Beyer, U., Diack, C. & Jaki, T. F., 11/2015, In: Pharmaceutical Statistics. 14, 6, p. 479-487 9 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Backfilling cohorts in phase I dose-escalation studies

Barnett, H., Boix, O., Kontos, D. & Jaki, T., 30/06/2023, In: Clinical Trials. 20, 3, p. 261-268 8 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Authors' reply to comments on "Estimation in AB/BA cross-over trials with application to bioequivalence studies with incomplete and complete data settings"

Jaki, T., Pallmann, P. & Wolfsegger, M. J., 30/12/2013, In: Statistics in Medicine. 32, 30, p. 5487-5488 2 p.

Research output: Contribution to Journal/Magazine › Comment/debate

Asymmetric inner wedge group sequential tests with applications to verifying whether effective drug concentrations are similar in adults and children

Hampson, L. V., Fisch, R., Van, L. M. & Jaki, T. F., 10/02/2017, In: Statistics in Medicine. 36, 3, p. 426-441 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Assessing systemic drug exposure in repeated dose toxicity studies in the case of complete and incomplete sampling.

Wolfsegger, M. J. & Jaki, T., 12/2009, In: Biometrical Journal. 51, 6, p. 1017-1026 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Assessing goodness-of-fit for evaluation of dose-proportionality

Wolfsegger, M. J., Bauer, A., Labes, D., Schütz, H., Vonk, R., Lang, B., Lehr, S., Jaki, T. F., Engl, W. & Hale, M. D., 31/03/2021, In: Pharmaceutical Statistics. 20, 2, p. 272-281 10 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Assessing differential effects: Applying regression mixture models to identify variations in the influence of family resources on academic achievement.

Van Horn, M. L., Jaki, T., Maysn, K., Ramey, S. L., Smith, J. A. & Antaramian, S., 09/2009, In: Developmental Psychology. 45, 5, p. 1298-1313 16 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Applying methods for personalized medicine to the treatment of alcohol use disorder

Kuhlemeier, A., Desai, Y., Tonigan, A., Witkiewitz, K., Jaki, T., Hsiao, Y-Y., Chang, C. & Van Horn, M. L., 30/04/2021, In: Journal of Consulting and Clinical Psychology. 89, 4, p. 288-300 13 p.

Research output: Contribution to Journal/Magazine › Journal article › peer-review