Although the popular protests that swept across the Middle East and North Africa in 2011 were short-lived, their long-term consequences are still resonating through the region a decade after their outbreak. Islamist movements have been affected in different ways by the drastic change in the political, social and geographical contexts in which they historically operated, highlighting the need for a renewed examination of these changed circumstances. Based on the case study of the Egyptian Muslim Brotherhood, we argue that three key factors need to be accounted for when studying Islamist movements in the aftermath of the 2011 uprisings. These are the dimension of exile; the increased role played by women and youth; and the emergence of cross-generational and cross-ideological alliances. The article analyzes these three factors through a comparative study of responses by Muslim Brotherhood and Muslim Sisterhood members to repression across Egypt, Turkey and the UK.