The cross sections for 2-, 3- and 4-jet production have been determined with the JADE detector, sited on thee + e −-storage ring PETRA. Data at s√=14 , 22, 35 and 44 GeV were compared to twoO(α s 2) QCD calculations. A first analysis was performed with uncorrected data using theO(α s 2) 3-jet matrix element calculation of Ellis, Ross and Terrano and the Lund String Monte Carlo program. In a second analysis the calculation of Kramer and Lampe was compared to corrected data. Both approaches gave a poor description of the data when the square of the momentum transferQ 2=s was used as the scale of the running coupling constant. The description improved when the renormalization scale was adjusted to the process studied. The data ware used to fix the best renormalization scale.