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A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes

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A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes. / Peng, Qiyao; Vermolen, Fred; Weihs, Daphne.
In: Biomechanics and modeling in mechanobiology, Vol. 20, No. 4, 31.08.2021, p. 1459-1475.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Peng, Q, Vermolen, F & Weihs, D 2021, 'A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes', Biomechanics and modeling in mechanobiology, vol. 20, no. 4, pp. 1459-1475. https://doi.org/10.1007/s10237-021-01456-2

APA

Peng, Q., Vermolen, F., & Weihs, D. (2021). A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes. Biomechanics and modeling in mechanobiology, 20(4), 1459-1475. https://doi.org/10.1007/s10237-021-01456-2

Vancouver

Peng Q, Vermolen F, Weihs D. A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes. Biomechanics and modeling in mechanobiology. 2021 Aug 31;20(4):1459-1475. Epub 2021 Apr 23. doi: 10.1007/s10237-021-01456-2

Author

Peng, Qiyao ; Vermolen, Fred ; Weihs, Daphne. / A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes. In: Biomechanics and modeling in mechanobiology. 2021 ; Vol. 20, No. 4. pp. 1459-1475.

Bibtex

@article{fbd80b9aaaf6436ab40c5ab36e4c3039,
title = "A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes",
abstract = "The phenomenological model for cell shape deformation and cell migration Chen (BMM 17:1429–1450, 2018), Vermolen and Gefen (BMM 12:301–323, 2012), is extended with the incorporation of cell traction forces and the evolution of cell equilibrium shapes as a result of cell differentiation. Plastic deformations of the extracellular matrix are modelled using morphoelasticity theory. The resulting partial differential differential equations are solved by the use of the finite element method. The paper treats various biological scenarios that entail cell migration and cell shape evolution. The experimental observations in Mak et al. (LC 13:340–348, 2013), where transmigration of cancer cells through narrow apertures is studied, are reproduced using a Monte Carlo framework.",
author = "Qiyao Peng and Fred Vermolen and Daphne Weihs",
year = "2021",
month = aug,
day = "31",
doi = "10.1007/s10237-021-01456-2",
language = "English",
volume = "20",
pages = "1459--1475",
journal = "Biomechanics and modeling in mechanobiology",
issn = "1617-7959",
publisher = "Springer Verlag",
number = "4",

}

RIS

TY - JOUR

T1 - A formalism for modelling traction forces and cell shape evolution during cell migration in various biomedical processes

AU - Peng, Qiyao

AU - Vermolen, Fred

AU - Weihs, Daphne

PY - 2021/8/31

Y1 - 2021/8/31

N2 - The phenomenological model for cell shape deformation and cell migration Chen (BMM 17:1429–1450, 2018), Vermolen and Gefen (BMM 12:301–323, 2012), is extended with the incorporation of cell traction forces and the evolution of cell equilibrium shapes as a result of cell differentiation. Plastic deformations of the extracellular matrix are modelled using morphoelasticity theory. The resulting partial differential differential equations are solved by the use of the finite element method. The paper treats various biological scenarios that entail cell migration and cell shape evolution. The experimental observations in Mak et al. (LC 13:340–348, 2013), where transmigration of cancer cells through narrow apertures is studied, are reproduced using a Monte Carlo framework.

AB - The phenomenological model for cell shape deformation and cell migration Chen (BMM 17:1429–1450, 2018), Vermolen and Gefen (BMM 12:301–323, 2012), is extended with the incorporation of cell traction forces and the evolution of cell equilibrium shapes as a result of cell differentiation. Plastic deformations of the extracellular matrix are modelled using morphoelasticity theory. The resulting partial differential differential equations are solved by the use of the finite element method. The paper treats various biological scenarios that entail cell migration and cell shape evolution. The experimental observations in Mak et al. (LC 13:340–348, 2013), where transmigration of cancer cells through narrow apertures is studied, are reproduced using a Monte Carlo framework.

UR - https://research.tudelft.nl/en/publications/bac7021c-7b0d-483d-8bb9-4fbca9f9a774

U2 - 10.1007/s10237-021-01456-2

DO - 10.1007/s10237-021-01456-2

M3 - Journal article

C2 - 33893558

VL - 20

SP - 1459

EP - 1475

JO - Biomechanics and modeling in mechanobiology

JF - Biomechanics and modeling in mechanobiology

SN - 1617-7959

IS - 4

ER -