A model for environmental sex reversal in fish.

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A model for environmental sex reversal in fish. / Hurley, M. A.; Matthiessen, P.; Pickering, A. D.
In: Journal of Theoretical Biology, Vol. 227, No. 2, 21.03.2004, p. 159-165.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Hurley, MA, Matthiessen, P & Pickering, AD 2004, 'A model for environmental sex reversal in fish.', Journal of Theoretical Biology, vol. 227, no. 2, pp. 159-165. https://doi.org/10.1016/j.jtbi.2003.10.010

APA

Hurley, M. A., Matthiessen, P., & Pickering, A. D. (2004). A model for environmental sex reversal in fish. Journal of Theoretical Biology, 227(2), 159-165. https://doi.org/10.1016/j.jtbi.2003.10.010

Vancouver

Hurley MA, Matthiessen P, Pickering AD. A model for environmental sex reversal in fish. Journal of Theoretical Biology. 2004 Mar 21;227(2):159-165. doi: 10.1016/j.jtbi.2003.10.010

Author

Hurley, M. A. ; Matthiessen, P. ; Pickering, A. D. / A model for environmental sex reversal in fish. In: Journal of Theoretical Biology. 2004 ; Vol. 227, No. 2. pp. 159-165.

Bibtex

@article{fff943348cc24ca59d595966ba9aa4c7,

title = "A model for environmental sex reversal in fish.",

abstract = "A mathematical model is presented which combines genetic XX-female/XY-male sex determination with environmental pressure for phenotypic sex reversal. This may occur when fishes are exposed to endocrine disrupters, specifically masculinization by exposure to androgens and feminization by exposure to estrogens. A generic model is derived for the sex ratio in successive generations and three special cases, with chronic and constant pressure to sex reverse, are discussed in detail. These show that, with extreme environmental pressure to masculinize, the male genotype is at risk of dying out but with less extreme pressure, masculinization will not be detectable since the proportion of phenotypic males becomes one-half. With feminization at any pressure to sex reverse, the male and female genotypes will be maintained in a stable sex ratio in which the proportion of genotypic males exceeds one-half and is close to one-half if YY offspring (eggs) are not viable. In converse, the model is also applicable to the genetic ZZ-male/ZW-female system of sex determination in fish. At present suitable data are not available with which to validate the model, but proposals are made for relevant experimental studies.",

keywords = "Endocrine disrupters, Masculinization, Feminization, Phenotypic sex ratio, Genotypic sex ratio",

author = "Hurley, {M. A.} and P. Matthiessen and Pickering, {A. D.}",

year = "2004",

month = mar,

day = "21",

doi = "10.1016/j.jtbi.2003.10.010",

language = "English",

volume = "227",

pages = "159--165",

journal = "Journal of Theoretical Biology",

issn = "0022-5193",

publisher = "Academic Press Inc.",

number = "2",

}

RIS

TY - JOUR

T1 - A model for environmental sex reversal in fish.

AU - Hurley, M. A.

AU - Matthiessen, P.

AU - Pickering, A. D.

PY - 2004/3/21

Y1 - 2004/3/21

N2 - A mathematical model is presented which combines genetic XX-female/XY-male sex determination with environmental pressure for phenotypic sex reversal. This may occur when fishes are exposed to endocrine disrupters, specifically masculinization by exposure to androgens and feminization by exposure to estrogens. A generic model is derived for the sex ratio in successive generations and three special cases, with chronic and constant pressure to sex reverse, are discussed in detail. These show that, with extreme environmental pressure to masculinize, the male genotype is at risk of dying out but with less extreme pressure, masculinization will not be detectable since the proportion of phenotypic males becomes one-half. With feminization at any pressure to sex reverse, the male and female genotypes will be maintained in a stable sex ratio in which the proportion of genotypic males exceeds one-half and is close to one-half if YY offspring (eggs) are not viable. In converse, the model is also applicable to the genetic ZZ-male/ZW-female system of sex determination in fish. At present suitable data are not available with which to validate the model, but proposals are made for relevant experimental studies.

AB - A mathematical model is presented which combines genetic XX-female/XY-male sex determination with environmental pressure for phenotypic sex reversal. This may occur when fishes are exposed to endocrine disrupters, specifically masculinization by exposure to androgens and feminization by exposure to estrogens. A generic model is derived for the sex ratio in successive generations and three special cases, with chronic and constant pressure to sex reverse, are discussed in detail. These show that, with extreme environmental pressure to masculinize, the male genotype is at risk of dying out but with less extreme pressure, masculinization will not be detectable since the proportion of phenotypic males becomes one-half. With feminization at any pressure to sex reverse, the male and female genotypes will be maintained in a stable sex ratio in which the proportion of genotypic males exceeds one-half and is close to one-half if YY offspring (eggs) are not viable. In converse, the model is also applicable to the genetic ZZ-male/ZW-female system of sex determination in fish. At present suitable data are not available with which to validate the model, but proposals are made for relevant experimental studies.

KW - Endocrine disrupters

KW - Masculinization

KW - Feminization

KW - Phenotypic sex ratio

KW - Genotypic sex ratio

U2 - 10.1016/j.jtbi.2003.10.010

DO - 10.1016/j.jtbi.2003.10.010

M3 - Journal article

VL - 227

SP - 159

EP - 165

JO - Journal of Theoretical Biology

JF - Journal of Theoretical Biology

SN - 0022-5193

IS - 2

ER -

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