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A physiological model of cerebral blood flow control

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A physiological model of cerebral blood flow control. / Banaji, Murad; Tachtsidis, Ilias; Delpy, David et al.
In: Mathematical Biosciences, Vol. 194, No. 2, 30.04.2005, p. 125-173.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Banaji, M, Tachtsidis, I, Delpy, D & Baigent, S 2005, 'A physiological model of cerebral blood flow control', Mathematical Biosciences, vol. 194, no. 2, pp. 125-173. https://doi.org/10.1016/j.mbs.2004.10.005

APA

Banaji, M., Tachtsidis, I., Delpy, D., & Baigent, S. (2005). A physiological model of cerebral blood flow control. Mathematical Biosciences, 194(2), 125-173. https://doi.org/10.1016/j.mbs.2004.10.005

Vancouver

Banaji M, Tachtsidis I, Delpy D, Baigent S. A physiological model of cerebral blood flow control. Mathematical Biosciences. 2005 Apr 30;194(2):125-173. doi: 10.1016/j.mbs.2004.10.005

Author

Banaji, Murad ; Tachtsidis, Ilias ; Delpy, David et al. / A physiological model of cerebral blood flow control. In: Mathematical Biosciences. 2005 ; Vol. 194, No. 2. pp. 125-173.

Bibtex

@article{f9c37d4532254e26a7bd991019a0c82c,
title = "A physiological model of cerebral blood flow control",
abstract = "The construction of a computational model of the human brain circulation is described. We combine an existing model of the biophysics of the circulatory system, a basic model of brain metabolic biochemistry, and a model of the functioning of vascular smooth muscle (VSM) into a single model. This represents a first attempt to understand how the numerous different feedback pathways by which cerebral blood flow is controlled interact with each other.The present work comprises the following: Descriptions of the physiology underlying the model; general comments on the processes by which this physiology is translated into mathematics; comments on parameter setting; and some simulation results. The simulations presented are preliminary, but show qualitative agreement between model behaviour and experimental results.",
author = "Murad Banaji and Ilias Tachtsidis and David Delpy and Stephen Baigent",
year = "2005",
month = apr,
day = "30",
doi = "10.1016/j.mbs.2004.10.005",
language = "English",
volume = "194",
pages = "125--173",
journal = "Mathematical Biosciences",
issn = "0025-5564",
publisher = "Elsevier Inc.",
number = "2",

}

RIS

TY - JOUR

T1 - A physiological model of cerebral blood flow control

AU - Banaji, Murad

AU - Tachtsidis, Ilias

AU - Delpy, David

AU - Baigent, Stephen

PY - 2005/4/30

Y1 - 2005/4/30

N2 - The construction of a computational model of the human brain circulation is described. We combine an existing model of the biophysics of the circulatory system, a basic model of brain metabolic biochemistry, and a model of the functioning of vascular smooth muscle (VSM) into a single model. This represents a first attempt to understand how the numerous different feedback pathways by which cerebral blood flow is controlled interact with each other.The present work comprises the following: Descriptions of the physiology underlying the model; general comments on the processes by which this physiology is translated into mathematics; comments on parameter setting; and some simulation results. The simulations presented are preliminary, but show qualitative agreement between model behaviour and experimental results.

AB - The construction of a computational model of the human brain circulation is described. We combine an existing model of the biophysics of the circulatory system, a basic model of brain metabolic biochemistry, and a model of the functioning of vascular smooth muscle (VSM) into a single model. This represents a first attempt to understand how the numerous different feedback pathways by which cerebral blood flow is controlled interact with each other.The present work comprises the following: Descriptions of the physiology underlying the model; general comments on the processes by which this physiology is translated into mathematics; comments on parameter setting; and some simulation results. The simulations presented are preliminary, but show qualitative agreement between model behaviour and experimental results.

U2 - 10.1016/j.mbs.2004.10.005

DO - 10.1016/j.mbs.2004.10.005

M3 - Journal article

VL - 194

SP - 125

EP - 173

JO - Mathematical Biosciences

JF - Mathematical Biosciences

SN - 0025-5564

IS - 2

ER -