Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - A short synthesis of the β-amyloid (Aβ) aggregation inhibitor 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran.
AU - Twyman, Lance J.
AU - Allsop, David
PY - 1999/12
Y1 - 1999/12
N2 - A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid, which is thought to be the underlying cause of Alzheimer's disease, is described. A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid protein is described.
AB - A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid, which is thought to be the underlying cause of Alzheimer's disease, is described. A short and convenient synthesis of 3-p-toluoyl-2-[4′-(3-diethylaminopropoxy)-phenyl]-benzofuran, an inhibitor of the aggregation of β-amyloid protein is described.
KW - Benzofurans
KW - heterocyclic
KW - intramolecular Wittig reaction
KW - β-amyloid
KW - Alzheimer's disease
U2 - 10.1016/S0040-4039(99)02030-4
DO - 10.1016/S0040-4039(99)02030-4
M3 - Journal article
VL - 40
SP - 9383
EP - 9384
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 52
ER -