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  • COOTE_Dihydropyridazines_2019_Revised

    Rights statement: This is the author’s version of a work that was accepted for publication in Tetrahedron Letters. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Tetrahedron Letters, 60, 22, 2019 DOI: 10.1016/j.tetlet.2019.04.054

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An efficient preparation of 1,2-dihydropyridazines through a Diels-Alder/palladium-catalysed elimination sequence

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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An efficient preparation of 1,2-dihydropyridazines through a Diels-Alder/palladium-catalysed elimination sequence. / Britten, T.K.; Akien, G.R.; Kemmitt, P.D. et al.
In: Tetrahedron Letters, Vol. 60, No. 22, 30.05.2019, p. 1498-1500.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Britten, TK, Akien, GR, Kemmitt, PD, Halcovitch, NR & Coote, SC 2019, 'An efficient preparation of 1,2-dihydropyridazines through a Diels-Alder/palladium-catalysed elimination sequence', Tetrahedron Letters, vol. 60, no. 22, pp. 1498-1500. https://doi.org/10.1016/j.tetlet.2019.04.054

APA

Britten, T. K., Akien, G. R., Kemmitt, P. D., Halcovitch, N. R., & Coote, S. C. (2019). An efficient preparation of 1,2-dihydropyridazines through a Diels-Alder/palladium-catalysed elimination sequence. Tetrahedron Letters, 60(22), 1498-1500. https://doi.org/10.1016/j.tetlet.2019.04.054

Vancouver

Britten TK, Akien GR, Kemmitt PD, Halcovitch NR, Coote SC. An efficient preparation of 1,2-dihydropyridazines through a Diels-Alder/palladium-catalysed elimination sequence. Tetrahedron Letters. 2019 May 30;60(22):1498-1500. Epub 2019 Apr 30. doi: 10.1016/j.tetlet.2019.04.054

Author

Britten, T.K. ; Akien, G.R. ; Kemmitt, P.D. et al. / An efficient preparation of 1,2-dihydropyridazines through a Diels-Alder/palladium-catalysed elimination sequence. In: Tetrahedron Letters. 2019 ; Vol. 60, No. 22. pp. 1498-1500.

Bibtex

@article{84594610ec364eaf88b5d1101a5a48e9,
title = "An efficient preparation of 1,2-dihydropyridazines through a Diels-Alder/palladium-catalysed elimination sequence",
abstract = "A convenient, scalable synthesis of 1,2-dihydropyridazines is presented, based on the Diels-Alder cycloaddition of 1-acetoxy-1,3-butadiene with a variety of azo compounds, followed by a palladium-catalysed elimination. The products are produced on multigram scale and the new method is particularly efficient and atom-economical when compared with previous preparations of 1,2-dihydropyridazines. ",
keywords = "Cycloadditions, Dihydropyridazine, Heterocycles, Palladium",
author = "T.K. Britten and G.R. Akien and P.D. Kemmitt and N.R. Halcovitch and S.C. Coote",
note = "This is the author{\textquoteright}s version of a work that was accepted for publication in Tetrahedron Letters. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Tetrahedron Letters, 60, 22, 2019 DOI: 10.1016/j.tetlet.2019.04.054",
year = "2019",
month = may,
day = "30",
doi = "10.1016/j.tetlet.2019.04.054",
language = "English",
volume = "60",
pages = "1498--1500",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Ltd",
number = "22",

}

RIS

TY - JOUR

T1 - An efficient preparation of 1,2-dihydropyridazines through a Diels-Alder/palladium-catalysed elimination sequence

AU - Britten, T.K.

AU - Akien, G.R.

AU - Kemmitt, P.D.

AU - Halcovitch, N.R.

AU - Coote, S.C.

N1 - This is the author’s version of a work that was accepted for publication in Tetrahedron Letters. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Tetrahedron Letters, 60, 22, 2019 DOI: 10.1016/j.tetlet.2019.04.054

PY - 2019/5/30

Y1 - 2019/5/30

N2 - A convenient, scalable synthesis of 1,2-dihydropyridazines is presented, based on the Diels-Alder cycloaddition of 1-acetoxy-1,3-butadiene with a variety of azo compounds, followed by a palladium-catalysed elimination. The products are produced on multigram scale and the new method is particularly efficient and atom-economical when compared with previous preparations of 1,2-dihydropyridazines.

AB - A convenient, scalable synthesis of 1,2-dihydropyridazines is presented, based on the Diels-Alder cycloaddition of 1-acetoxy-1,3-butadiene with a variety of azo compounds, followed by a palladium-catalysed elimination. The products are produced on multigram scale and the new method is particularly efficient and atom-economical when compared with previous preparations of 1,2-dihydropyridazines.

KW - Cycloadditions

KW - Dihydropyridazine

KW - Heterocycles

KW - Palladium

U2 - 10.1016/j.tetlet.2019.04.054

DO - 10.1016/j.tetlet.2019.04.054

M3 - Journal article

VL - 60

SP - 1498

EP - 1500

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 22

ER -