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An electrochemiluminescence biosensor based on Graphitic carbon nitride luminescence quenching for detection of AFB

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An electrochemiluminescence biosensor based on Graphitic carbon nitride luminescence quenching for detection of AFB. / Tian, D.; Wang, J.; Zhuang, Q. et al.
In: Food Chemistry, Vol. 404, No. Pt A, 134183, 15.03.2023.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Tian, D, Wang, J, Zhuang, Q, Wu, S, Yu, Y & Ding, K 2023, 'An electrochemiluminescence biosensor based on Graphitic carbon nitride luminescence quenching for detection of AFB', Food Chemistry, vol. 404, no. Pt A, 134183. https://doi.org/10.1016/j.foodchem.2022.134183

APA

Tian, D., Wang, J., Zhuang, Q., Wu, S., Yu, Y., & Ding, K. (2023). An electrochemiluminescence biosensor based on Graphitic carbon nitride luminescence quenching for detection of AFB. Food Chemistry, 404(Pt A), Article 134183. https://doi.org/10.1016/j.foodchem.2022.134183

Vancouver

Tian D, Wang J, Zhuang Q, Wu S, Yu Y, Ding K. An electrochemiluminescence biosensor based on Graphitic carbon nitride luminescence quenching for detection of AFB. Food Chemistry. 2023 Mar 15;404(Pt A):134183. Epub 2022 Oct 11. doi: 10.1016/j.foodchem.2022.134183

Author

Tian, D. ; Wang, J. ; Zhuang, Q. et al. / An electrochemiluminescence biosensor based on Graphitic carbon nitride luminescence quenching for detection of AFB. In: Food Chemistry. 2023 ; Vol. 404, No. Pt A.

Bibtex

@article{3c21485c7b6543afa0fe91a4db2b97c1,
title = "An electrochemiluminescence biosensor based on Graphitic carbon nitride luminescence quenching for detection of AFB",
abstract = "Based on graphite-like carbon nitride (g-CN) nanocomposites coupled with aptamer, a regenerable electrochemiluminescence (ECL) biosensor is developed for the quantitative detection of aflatoxin B 1 (AFB 1). In the existence of AFB 1, the structure of the aptamer changed into a loop, and the original ECL intensity was reduced owing to the enhancement of luminescence quenching between the ferrocene modified at the end of the aptamer and the luminescent substrate g-CN. Moreover, AFB 1 with oxidation state could also react with high energy state g-CN, leading to further reduction of the electrochemiluminescence signal. At optimum conditions, ECL intensity was decreased in linearity with an AFB 1 concentration range from 0.005 ng/mL to 10 ng/mL, and the minimum detectable concentration was down to 0.005 ng/mL, which realized trace detection demand with high sensitivity. It was selective for AFB 1 and its performance had been verified on rice samples, which indicated a promising applying prospect of non-enzymatic electrochemiluminescence AFB 1 detection.",
keywords = "Aflatoxin B1, Electrochemiluminesce biosensor, Graphitic carbon nitride, Luminescence quenching",
author = "D. Tian and J. Wang and Q. Zhuang and S. Wu and Y. Yu and K. Ding",
year = "2023",
month = mar,
day = "15",
doi = "10.1016/j.foodchem.2022.134183",
language = "English",
volume = "404",
journal = "Food Chemistry",
issn = "0308-8146",
publisher = "Elsevier Limited",
number = "Pt A",

}

RIS

TY - JOUR

T1 - An electrochemiluminescence biosensor based on Graphitic carbon nitride luminescence quenching for detection of AFB

AU - Tian, D.

AU - Wang, J.

AU - Zhuang, Q.

AU - Wu, S.

AU - Yu, Y.

AU - Ding, K.

PY - 2023/3/15

Y1 - 2023/3/15

N2 - Based on graphite-like carbon nitride (g-CN) nanocomposites coupled with aptamer, a regenerable electrochemiluminescence (ECL) biosensor is developed for the quantitative detection of aflatoxin B 1 (AFB 1). In the existence of AFB 1, the structure of the aptamer changed into a loop, and the original ECL intensity was reduced owing to the enhancement of luminescence quenching between the ferrocene modified at the end of the aptamer and the luminescent substrate g-CN. Moreover, AFB 1 with oxidation state could also react with high energy state g-CN, leading to further reduction of the electrochemiluminescence signal. At optimum conditions, ECL intensity was decreased in linearity with an AFB 1 concentration range from 0.005 ng/mL to 10 ng/mL, and the minimum detectable concentration was down to 0.005 ng/mL, which realized trace detection demand with high sensitivity. It was selective for AFB 1 and its performance had been verified on rice samples, which indicated a promising applying prospect of non-enzymatic electrochemiluminescence AFB 1 detection.

AB - Based on graphite-like carbon nitride (g-CN) nanocomposites coupled with aptamer, a regenerable electrochemiluminescence (ECL) biosensor is developed for the quantitative detection of aflatoxin B 1 (AFB 1). In the existence of AFB 1, the structure of the aptamer changed into a loop, and the original ECL intensity was reduced owing to the enhancement of luminescence quenching between the ferrocene modified at the end of the aptamer and the luminescent substrate g-CN. Moreover, AFB 1 with oxidation state could also react with high energy state g-CN, leading to further reduction of the electrochemiluminescence signal. At optimum conditions, ECL intensity was decreased in linearity with an AFB 1 concentration range from 0.005 ng/mL to 10 ng/mL, and the minimum detectable concentration was down to 0.005 ng/mL, which realized trace detection demand with high sensitivity. It was selective for AFB 1 and its performance had been verified on rice samples, which indicated a promising applying prospect of non-enzymatic electrochemiluminescence AFB 1 detection.

KW - Aflatoxin B1

KW - Electrochemiluminesce biosensor

KW - Graphitic carbon nitride

KW - Luminescence quenching

U2 - 10.1016/j.foodchem.2022.134183

DO - 10.1016/j.foodchem.2022.134183

M3 - Journal article

VL - 404

JO - Food Chemistry

JF - Food Chemistry

SN - 0308-8146

IS - Pt A

M1 - 134183

ER -