Rights statement: Published version at https://doi.org/10.9734/ijmpcr/2018/v11i530093
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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Anatomical aspects of Mycobacterium tuberculosis–associated destructive cranial lesions
AU - Wessels, Quenton
AU - Taylor, Adam Michael
AU - Correia, Jc
N1 - Published version at https://doi.org/10.9734/ijmpcr/2018/v11i530093
PY - 2019/2/28
Y1 - 2019/2/28
N2 - The authors report two cases of destructive cranial lesions associated with Mycobacterium tuberculosis–HIV coinfection in a male and female cadaver. Both cadavers were of African origin, from the Western Cape, South Africa. The authors present grossly abnormal tuberculosis–associated lesions of the anterior and middle cranial fossae, involving the ethmoid and sphenoid bones. Both individuals presented with tubercular intrasellar masses and obliteration of the paranasal sinuses. Current literature on cases such as these are extremely rare and others typically focus on lesions of the calvarium. Here we report on the gross anatomical findings as well as the relevant anatomical aspects of the probable aetiology. Both cases presented here hold interest for medical professionals in Africa and other geographic regions. It further illustrates the importance of understanding the venous drainage of the paranasal sinuses when considering the manifestation and treatment of extrapulmonary TB.
AB - The authors report two cases of destructive cranial lesions associated with Mycobacterium tuberculosis–HIV coinfection in a male and female cadaver. Both cadavers were of African origin, from the Western Cape, South Africa. The authors present grossly abnormal tuberculosis–associated lesions of the anterior and middle cranial fossae, involving the ethmoid and sphenoid bones. Both individuals presented with tubercular intrasellar masses and obliteration of the paranasal sinuses. Current literature on cases such as these are extremely rare and others typically focus on lesions of the calvarium. Here we report on the gross anatomical findings as well as the relevant anatomical aspects of the probable aetiology. Both cases presented here hold interest for medical professionals in Africa and other geographic regions. It further illustrates the importance of understanding the venous drainage of the paranasal sinuses when considering the manifestation and treatment of extrapulmonary TB.
KW - mycobacterium tuberculosis
KW - HIV
KW - coinfection
KW - cranial lesions
KW - paranasal sinuses
U2 - 10.9734/ijmpcr/2018/v11i530093
DO - 10.9734/ijmpcr/2018/v11i530093
M3 - Journal article
VL - 11
SP - 1
EP - 5
JO - International Journal of Medical and Pharmaceutical Case Reports
JF - International Journal of Medical and Pharmaceutical Case Reports
SN - 2394-109X
IS - 5
ER -