Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Asymmetric aziridine synthesis via aza-Darzens reaction of bromoacylcamphorsultam
AU - Cantrill, Alex A.
AU - Hall, Lee D.
AU - Jarvis, Ashley N.
AU - Osborn, Helen M.I.
AU - Raphy, Jenny
AU - Sweeney, J. B.
PY - 1996/1/1
Y1 - 1996/1/1
N2 - The aza-Darzens reaction of the chiral enolate derived from bromoacetylcamphorsultam 1 with N-(diphenylphosphinyl)aryl- and tert-butyl-methanimines proceeds in good yield to give cis-N-(diphenylphosphinyl)aziridinylcarbonyl sultams with high de. Monochiral cis-aziridinecarboxylates may be obtained in acceptable yield by hydrolysis of these sultams.
AB - The aza-Darzens reaction of the chiral enolate derived from bromoacetylcamphorsultam 1 with N-(diphenylphosphinyl)aryl- and tert-butyl-methanimines proceeds in good yield to give cis-N-(diphenylphosphinyl)aziridinylcarbonyl sultams with high de. Monochiral cis-aziridinecarboxylates may be obtained in acceptable yield by hydrolysis of these sultams.
U2 - 10.1039/cc9960002631
DO - 10.1039/cc9960002631
M3 - Journal article
AN - SCOPUS:0001932039
VL - 1996
SP - 2631
EP - 2632
JO - Chemical Communications
JF - Chemical Communications
SN - 1359-7345
IS - 23
ER -