Final published version
Licence: CC BY: Creative Commons Attribution 4.0 International License
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Bioactive Nano Hydroxyapatites for Orbital Floor Repair and Regeneration
AU - Talari, Abdullah
AU - Rehman, Ihtesham Ur
AU - Alhamoudi, Fahad
AU - Almoshawah, Yasser
AU - Reilly, G.C.
AU - Chaudhry, Aqif Anwar
PY - 2021/5/17
Y1 - 2021/5/17
N2 - Bioactive nano-hydroxyapatites have been synthesised for orbital floor repair and regeneration. Hydroxyapatite (HA) is widely used for bone repair and regeneration. It is composed of multiple anionic and cationic species, such ascarbonate, fluoride, phosphate, sodium, magnesium, silicon and citrate. However, the development of bioactive materials that can repair and regenerate bone is crucial for orbital floor fracture repair. Different ionic-substituted hydroxyapatites that included carbonate, fluoride and citrate were prepared by using a low-temperature hydrothermal flow process and their chemical and physical properties evaluated. Biological properties were evaluated by analysing cell viability of these synthesised materials by Alamar Blue cell metabolic activity assay with two different cell lines (MG63 and HTERT-BMSC’s). Results confirmed that ionic substitution with fluoride and citrate improved biocompatibility andcell viability of synthesised hydroxyapatites.
AB - Bioactive nano-hydroxyapatites have been synthesised for orbital floor repair and regeneration. Hydroxyapatite (HA) is widely used for bone repair and regeneration. It is composed of multiple anionic and cationic species, such ascarbonate, fluoride, phosphate, sodium, magnesium, silicon and citrate. However, the development of bioactive materials that can repair and regenerate bone is crucial for orbital floor fracture repair. Different ionic-substituted hydroxyapatites that included carbonate, fluoride and citrate were prepared by using a low-temperature hydrothermal flow process and their chemical and physical properties evaluated. Biological properties were evaluated by analysing cell viability of these synthesised materials by Alamar Blue cell metabolic activity assay with two different cell lines (MG63 and HTERT-BMSC’s). Results confirmed that ionic substitution with fluoride and citrate improved biocompatibility andcell viability of synthesised hydroxyapatites.
M3 - Journal article
VL - 4
JO - Journal of Nanomedicine
JF - Journal of Nanomedicine
SN - 2578-8760
IS - 1
M1 - 1038
ER -