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Characterisation of an octasaccharide chondroitin sulphate linkage region fragment

Research output: Contribution to Journal/MagazineJournal articlepeer-review

<mark>Journal publication date</mark>1/12/1999
<mark>Journal</mark>Carbohydrate Letters
Issue number5
Number of pages8
Pages (from-to)381-388
Publication StatusPublished
<mark>Original language</mark>English


We report the isolation and characterisation of an octasaccharide derived from the chondroitin sulphate linkage region of 6-8-year-old bovine articular cartilage aggrecan following digestion with chondroitin ABC endolyase. Characterisation by a novel high pH anion exchange chromatography method, identified the following structure for the chondroitin sulphate linkage region octasaccharide: ΔUAβ(1-3)GalNAc6Sβ(1-4)GlcAβ(1- 3)GalNAc6Sβ(1-4)GlcAβ(1-3)Galβ(1-3)Galβ(1-4)Xyl.