Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Characterisation of an octasaccharide chondroitin sulphate linkage region fragment
AU - Lauder, R. M.
AU - Huckerby, T. N.
AU - Nieduszynski, I. A.
PY - 1999/12/1
Y1 - 1999/12/1
N2 - We report the isolation and characterisation of an octasaccharide derived from the chondroitin sulphate linkage region of 6-8-year-old bovine articular cartilage aggrecan following digestion with chondroitin ABC endolyase. Characterisation by a novel high pH anion exchange chromatography method, identified the following structure for the chondroitin sulphate linkage region octasaccharide: ΔUAβ(1-3)GalNAc6Sβ(1-4)GlcAβ(1- 3)GalNAc6Sβ(1-4)GlcAβ(1-3)Galβ(1-3)Galβ(1-4)Xyl.
AB - We report the isolation and characterisation of an octasaccharide derived from the chondroitin sulphate linkage region of 6-8-year-old bovine articular cartilage aggrecan following digestion with chondroitin ABC endolyase. Characterisation by a novel high pH anion exchange chromatography method, identified the following structure for the chondroitin sulphate linkage region octasaccharide: ΔUAβ(1-3)GalNAc6Sβ(1-4)GlcAβ(1- 3)GalNAc6Sβ(1-4)GlcAβ(1-3)Galβ(1-3)Galβ(1-4)Xyl.
KW - Aggrecan
KW - Chondroitin sulphate/sulfate
KW - Linkage region
M3 - Journal article
AN - SCOPUS:0033430988
VL - 3
SP - 381
EP - 388
JO - Carbohydrate Letters
JF - Carbohydrate Letters
SN - 1073-5070
IS - 5
ER -