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Characterisation of an octasaccharide chondroitin sulphate linkage region fragment

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Characterisation of an octasaccharide chondroitin sulphate linkage region fragment. / Lauder, R. M.; Huckerby, T. N.; Nieduszynski, I. A.
In: Carbohydrate Letters, Vol. 3, No. 5, 01.12.1999, p. 381-388.

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@article{c19088fe4c5a4d0db68fccc0835856da,
title = "Characterisation of an octasaccharide chondroitin sulphate linkage region fragment",
abstract = "We report the isolation and characterisation of an octasaccharide derived from the chondroitin sulphate linkage region of 6-8-year-old bovine articular cartilage aggrecan following digestion with chondroitin ABC endolyase. Characterisation by a novel high pH anion exchange chromatography method, identified the following structure for the chondroitin sulphate linkage region octasaccharide: ΔUAβ(1-3)GalNAc6Sβ(1-4)GlcAβ(1- 3)GalNAc6Sβ(1-4)GlcAβ(1-3)Galβ(1-3)Galβ(1-4)Xyl.",
keywords = "Aggrecan, Chondroitin sulphate/sulfate, Linkage region",
author = "Lauder, {R. M.} and Huckerby, {T. N.} and Nieduszynski, {I. A.}",
year = "1999",
month = dec,
day = "1",
language = "English",
volume = "3",
pages = "381--388",
journal = "Carbohydrate Letters",
issn = "1073-5070",
publisher = "Harwood Academic Publishers",
number = "5",

}

RIS

TY - JOUR

T1 - Characterisation of an octasaccharide chondroitin sulphate linkage region fragment

AU - Lauder, R. M.

AU - Huckerby, T. N.

AU - Nieduszynski, I. A.

PY - 1999/12/1

Y1 - 1999/12/1

N2 - We report the isolation and characterisation of an octasaccharide derived from the chondroitin sulphate linkage region of 6-8-year-old bovine articular cartilage aggrecan following digestion with chondroitin ABC endolyase. Characterisation by a novel high pH anion exchange chromatography method, identified the following structure for the chondroitin sulphate linkage region octasaccharide: ΔUAβ(1-3)GalNAc6Sβ(1-4)GlcAβ(1- 3)GalNAc6Sβ(1-4)GlcAβ(1-3)Galβ(1-3)Galβ(1-4)Xyl.

AB - We report the isolation and characterisation of an octasaccharide derived from the chondroitin sulphate linkage region of 6-8-year-old bovine articular cartilage aggrecan following digestion with chondroitin ABC endolyase. Characterisation by a novel high pH anion exchange chromatography method, identified the following structure for the chondroitin sulphate linkage region octasaccharide: ΔUAβ(1-3)GalNAc6Sβ(1-4)GlcAβ(1- 3)GalNAc6Sβ(1-4)GlcAβ(1-3)Galβ(1-3)Galβ(1-4)Xyl.

KW - Aggrecan

KW - Chondroitin sulphate/sulfate

KW - Linkage region

M3 - Journal article

AN - SCOPUS:0033430988

VL - 3

SP - 381

EP - 388

JO - Carbohydrate Letters

JF - Carbohydrate Letters

SN - 1073-5070

IS - 5

ER -