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Cognitive aids for people with early stage dementia versus treatment as usual (Dementia Early Stage Cognitive Aids New Trial [DESCANT]): study protocol for a randomised controlled trial

Research output: Contribution to Journal/MagazineJournal articlepeer-review

  • Helen Chester
  • Paul Clarkson
  • Linda M Davies
  • Given Names Deactivated Family Name Deactivated
  • Muhammad Saiful Islam
  • Narinder Kapur
  • Martin Orrell
  • Julie Peconi
  • Rosa Pitts
  • Fiona Poland
  • Ian Russell
  • David Challis
  • HoSt-D (Home Support in Dementia) Programme Management Group
Article number546
<mark>Journal publication date</mark>10/10/2018
Number of pages11
Publication StatusPublished
<mark>Original language</mark>English


Background: There is a growing need for an evidence-based approach to home support for people with dementia and their carers following diagnosis but research on the effectiveness and cost-effectiveness of different approaches is sparse. The Dementia Early Stage Cognitive Aids New Trial [DESCANT] will evaluate the clinical and cost-effectiveness of a range of memory aids, training and support to people with mild to moderate dementia and their carers at home and compares that intervention with treatment as usual.

Methods/Design: This is a multi-site, pragmatic randomised trial preceded by a feasibility study and internal pilot. We aim to allocate at random 360 pairs comprising a person with mild to moderate dementia and an identified carer between the DESCANT intervention and treatment as usual. We assess participants at baseline, 13 and 26 weeks. The primary outcome measure is the Bristol Activities of Daily Living Scale; other participant outcomes include cognition, quality of life, activities of daily living and social networking; and carer outcomes include quality of life, sense of competence and mental health. To enhance this quantitative evaluation we are conducting a qualitative component and a process evaluation to assess the implementation process and identify contextual factors associated with variation.

Discussion: The DESCANT intervention reflects current policy to enhance the capabilities of people with dementia after diagnosis, and their carers. If it is clinically and cost-effective, its modest nature and cost will enhance the likelihood of it being incorporated into mainstream practice.