TY - JOUR

T1 - Cognitive aids for people with early stage dementia versus treatment as usual (Dementia Early Stage Cognitive Aids New Trial [DESCANT])

T2 - study protocol for a randomised controlled trial

AU - Chester, Helen

AU - Clarkson, Paul

AU - Davies, Linda M

AU - Deactivated, Given Names Deactivated Family Name

AU - Islam, Muhammad Saiful

AU - Kapur, Narinder

AU - Orrell, Martin

AU - Peconi, Julie

AU - Pitts, Rosa

AU - Poland, Fiona

AU - Russell, Ian

AU - Challis, David

AU - Group, HoSt-D (Home Support in Dementia) Programme Management

PY - 2018/10/10

Y1 - 2018/10/10

N2 - Background: There is a growing need for an evidence-based approach to home support for people with dementia and their carers following diagnosis but research on the effectiveness and cost-effectiveness of different approaches is sparse. The Dementia Early Stage Cognitive Aids New Trial [DESCANT] will evaluate the clinical and cost-effectiveness of a range of memory aids, training and support to people with mild to moderate dementia and their carers at home and compares that intervention with treatment as usual.Methods/Design: This is a multi-site, pragmatic randomised trial preceded by a feasibility study and internal pilot. We aim to allocate at random 360 pairs comprising a person with mild to moderate dementia and an identified carer between the DESCANT intervention and treatment as usual. We assess participants at baseline, 13 and 26 weeks. The primary outcome measure is the Bristol Activities of Daily Living Scale; other participant outcomes include cognition, quality of life, activities of daily living and social networking; and carer outcomes include quality of life, sense of competence and mental health. To enhance this quantitative evaluation we are conducting a qualitative component and a process evaluation to assess the implementation process and identify contextual factors associated with variation. Discussion: The DESCANT intervention reflects current policy to enhance the capabilities of people with dementia after diagnosis, and their carers. If it is clinically and cost-effective, its modest nature and cost will enhance the likelihood of it being incorporated into mainstream practice.

AB - Background: There is a growing need for an evidence-based approach to home support for people with dementia and their carers following diagnosis but research on the effectiveness and cost-effectiveness of different approaches is sparse. The Dementia Early Stage Cognitive Aids New Trial [DESCANT] will evaluate the clinical and cost-effectiveness of a range of memory aids, training and support to people with mild to moderate dementia and their carers at home and compares that intervention with treatment as usual.Methods/Design: This is a multi-site, pragmatic randomised trial preceded by a feasibility study and internal pilot. We aim to allocate at random 360 pairs comprising a person with mild to moderate dementia and an identified carer between the DESCANT intervention and treatment as usual. We assess participants at baseline, 13 and 26 weeks. The primary outcome measure is the Bristol Activities of Daily Living Scale; other participant outcomes include cognition, quality of life, activities of daily living and social networking; and carer outcomes include quality of life, sense of competence and mental health. To enhance this quantitative evaluation we are conducting a qualitative component and a process evaluation to assess the implementation process and identify contextual factors associated with variation. Discussion: The DESCANT intervention reflects current policy to enhance the capabilities of people with dementia after diagnosis, and their carers. If it is clinically and cost-effective, its modest nature and cost will enhance the likelihood of it being incorporated into mainstream practice.

KW - Early-stage dementia

KW - Memory aids

KW - Community

KW - Psychosocial outcomes

KW - Quality of life

KW - Effectiveness

KW - Cost-effectiveness

KW - Pragmatic randomised trial

KW - Process evaluation

UR - https://pureprojects.ppad.man.ac.uk/portal/en/publications/cognitive-aids-for-people-with-early-stage-dementia-versus-treatment-as-usual-dementia-early-stage-cognitive-aids-new-trial-descant-study-protocol-for-a-randomised-controlled-trial(e7592c47-b175-4a41-a879-e5a01c97198f).html

U2 - 10.1186/s13063-018-2933-8

DO - 10.1186/s13063-018-2933-8

M3 - Journal article

VL - 19

JO - Trials

JF - Trials

SN - 1745-6215

M1 - 546

ER -