Building on recent progress in constructing derivations on Fourier algebras, we provide the first examples of locally compact groups whose Fourier algebras support non-zero, alternating 2-cocycles; this is the first step in a larger project. Although such 2-cocycles can never be completely bounded, the operator space structure on the Fourier algebra plays a crucial role in our construction, as does the opposite operator space structure.

Our construction has two main technical ingredients: we observe that certain estimates from [H. H. Lee, J. Ludwig, E. Samei, N. Spronk, Weak amenability of Fourier algebras and local synthesis of the anti-diagonal, Adv. Math., 292 (2016)] yield derivations that are "co-completely bounded" as maps from various Fourier algebras to their duals; and we establish a twisted inclusion result for certain operator space tensor products, which may be of independent interest.