Final published version
Licence: CC BY-NC: Creative Commons Attribution-NonCommercial 4.0 International License
Research output: Contribution to Journal/Magazine › Journal article › peer-review
<mark>Journal publication date</mark> | 04/2018 |
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<mark>Journal</mark> | Microbial Genomics |
Issue number | 4 |
Volume | 2018 |
Number of pages | 8 |
Publication Status | Published |
Early online date | 10/04/18 |
<mark>Original language</mark> | English |
Based on complete bacterial genome sequence data, we demonstrate a correlation between bacterial chromosome length and the G+C content of the genome, with longer genomes having higher G+C contents. The correlation value decreases at shorter genome sizes, where there is a wider spread of G+C values. However, although significant (P<0.001), the correlation value (Pearson R=0.58) suggests that other factors also have a significant influence. A similar pattern was seen for plasmids; longer plasmids had higher G+C values, although the large number of shorter plasmids had a wide spread of G+C values. There was also a significant (P<0.0001) correlation between the G+C content of plasmids and the G+C content of their bacterial host. Conversely, the G+C content of bacteriophages tended to reduce with larger genome sizes, and although there was a correlation between host genome G+C content and that of the bacteriophage, it was not as strong as that seen between plasmids and their hosts.