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Economic analysis of a freeze-drying cycle

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Economic analysis of a freeze-drying cycle. / Stratta, Lorenzo; Capozzi, Luigi C.; Franzino, Simone et al.
In: Processes, Vol. 8, No. 11, 1399, 02.11.2020, p. 1-17.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Stratta, L, Capozzi, LC, Franzino, S & Pisano, R 2020, 'Economic analysis of a freeze-drying cycle', Processes, vol. 8, no. 11, 1399, pp. 1-17. https://doi.org/10.3390/pr8111399

APA

Stratta, L., Capozzi, L. C., Franzino, S., & Pisano, R. (2020). Economic analysis of a freeze-drying cycle. Processes, 8(11), 1-17. Article 1399. https://doi.org/10.3390/pr8111399

Vancouver

Stratta L, Capozzi LC, Franzino S, Pisano R. Economic analysis of a freeze-drying cycle. Processes. 2020 Nov 2;8(11):1-17. 1399. doi: 10.3390/pr8111399

Author

Stratta, Lorenzo ; Capozzi, Luigi C. ; Franzino, Simone et al. / Economic analysis of a freeze-drying cycle. In: Processes. 2020 ; Vol. 8, No. 11. pp. 1-17.

Bibtex

@article{70dcfb6bd3bb433f8a0b49eedf21ad11,
title = "Economic analysis of a freeze-drying cycle",
abstract = "Freeze-drying has always been considered an extremely expensive procedure to dehydrate food or pharmaceutical products, and for this reason, it has been employed only if strictly necessary or when the high added value of the final product could justify the costs. However, little effort has been made to analyze the factors that make this technology so unaffordable. In this work, a model was proposed to calculate in detail the operational (OC) and capital costs (CC) of a freeze-drying cycle and an evaluation of the process bottlenecks was made. The main result is that the process itself, contrary to the classic belief, is not the most expensive part of freeze-drying, while the initial investment is the real limiting factor. Under this consideration, the optimization of a freeze-drying cycle should be formulated in order to fit more cycles in the lifespan of the apparatus, instead of merely reducing the power consumption of the machine.",
keywords = "Costs analysis, Freeze-drying, Lyophilization, Optimization",
author = "Lorenzo Stratta and Capozzi, {Luigi C.} and Simone Franzino and Roberto Pisano",
note = "Publisher Copyright: {\textcopyright} 2020 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2020",
month = nov,
day = "2",
doi = "10.3390/pr8111399",
language = "English",
volume = "8",
pages = "1--17",
journal = "Processes",
issn = "2227-9717",
publisher = "MDPI AG",
number = "11",

}

RIS

TY - JOUR

T1 - Economic analysis of a freeze-drying cycle

AU - Stratta, Lorenzo

AU - Capozzi, Luigi C.

AU - Franzino, Simone

AU - Pisano, Roberto

N1 - Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2020/11/2

Y1 - 2020/11/2

N2 - Freeze-drying has always been considered an extremely expensive procedure to dehydrate food or pharmaceutical products, and for this reason, it has been employed only if strictly necessary or when the high added value of the final product could justify the costs. However, little effort has been made to analyze the factors that make this technology so unaffordable. In this work, a model was proposed to calculate in detail the operational (OC) and capital costs (CC) of a freeze-drying cycle and an evaluation of the process bottlenecks was made. The main result is that the process itself, contrary to the classic belief, is not the most expensive part of freeze-drying, while the initial investment is the real limiting factor. Under this consideration, the optimization of a freeze-drying cycle should be formulated in order to fit more cycles in the lifespan of the apparatus, instead of merely reducing the power consumption of the machine.

AB - Freeze-drying has always been considered an extremely expensive procedure to dehydrate food or pharmaceutical products, and for this reason, it has been employed only if strictly necessary or when the high added value of the final product could justify the costs. However, little effort has been made to analyze the factors that make this technology so unaffordable. In this work, a model was proposed to calculate in detail the operational (OC) and capital costs (CC) of a freeze-drying cycle and an evaluation of the process bottlenecks was made. The main result is that the process itself, contrary to the classic belief, is not the most expensive part of freeze-drying, while the initial investment is the real limiting factor. Under this consideration, the optimization of a freeze-drying cycle should be formulated in order to fit more cycles in the lifespan of the apparatus, instead of merely reducing the power consumption of the machine.

KW - Costs analysis

KW - Freeze-drying

KW - Lyophilization

KW - Optimization

U2 - 10.3390/pr8111399

DO - 10.3390/pr8111399

M3 - Journal article

AN - SCOPUS:85095126450

VL - 8

SP - 1

EP - 17

JO - Processes

JF - Processes

SN - 2227-9717

IS - 11

M1 - 1399

ER -