Home > Research > Publications & Outputs > End-resection at DNA double-strand breaks in th...

Research

Associated organisational unit

Links

Text available via DOI:

Keywords

View graph of relations

End-resection at DNA double-strand breaks in the three domains of life

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Published

Standard

End-resection at DNA double-strand breaks in the three domains of life. / Blackwood, John K.; Rzechorzek, Neil J.; Bray, Sian M. et al.
In: Biochemical Society Transactions, Vol. 41, No. 1, 01.02.2013, p. 314-320.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Blackwood, JK, Rzechorzek, NJ, Bray, SM, Maman, JD, Pellegrini, L & Robinson, NP 2013, 'End-resection at DNA double-strand breaks in the three domains of life', Biochemical Society Transactions, vol. 41, no. 1, pp. 314-320. https://doi.org/10.1042/BST20120307

APA

Blackwood, J. K., Rzechorzek, N. J., Bray, S. M., Maman, J. D., Pellegrini, L., & Robinson, N. P. (2013). End-resection at DNA double-strand breaks in the three domains of life. Biochemical Society Transactions, 41(1), 314-320. https://doi.org/10.1042/BST20120307

Vancouver

Blackwood JK, Rzechorzek NJ, Bray SM, Maman JD, Pellegrini L, Robinson NP. End-resection at DNA double-strand breaks in the three domains of life. Biochemical Society Transactions. 2013 Feb 1;41(1):314-320. doi: 10.1042/BST20120307

Author

Blackwood, John K. ; Rzechorzek, Neil J. ; Bray, Sian M. et al. / End-resection at DNA double-strand breaks in the three domains of life. In: Biochemical Society Transactions. 2013 ; Vol. 41, No. 1. pp. 314-320.

Bibtex

@article{44cc38770fc046bfb0df185b114be3f2,
title = "End-resection at DNA double-strand breaks in the three domains of life",
abstract = "During DNA repair by HR (homologous recombination), the ends of a DNA DSB (double-strand break) must be resected to generate single-stranded tails, which are required for strand invasion and exchange with homologous chromosomes. This 5'-3' end-resection of the DNA duplex is an essential process, conserved across all three domains of life: the bacteria, eukaryota and archaea. In the present review, we examine the numerous and redundant helicase and nuclease systems that function as the enzymatic analogues for this crucial process in the three major phylogenetic divisions.",
keywords = "DNA, DNA Damage, DNA, Archaeal, DNA, Bacterial, Eukaryotic Cells, Phylogeny, Journal Article, Research Support, Non-U.S. Gov't, Review",
author = "Blackwood, {John K.} and Rzechorzek, {Neil J.} and Bray, {Sian M.} and Maman, {Joseph D.} and Luca Pellegrini and Robinson, {Nicholas P.}",
year = "2013",
month = feb,
day = "1",
doi = "10.1042/BST20120307",
language = "English",
volume = "41",
pages = "314--320",
journal = "Biochemical Society Transactions",
issn = "0300-5127",
publisher = "Portland Press Ltd.",
number = "1",

}

RIS

TY - JOUR

T1 - End-resection at DNA double-strand breaks in the three domains of life

AU - Blackwood, John K.

AU - Rzechorzek, Neil J.

AU - Bray, Sian M.

AU - Maman, Joseph D.

AU - Pellegrini, Luca

AU - Robinson, Nicholas P.

PY - 2013/2/1

Y1 - 2013/2/1

N2 - During DNA repair by HR (homologous recombination), the ends of a DNA DSB (double-strand break) must be resected to generate single-stranded tails, which are required for strand invasion and exchange with homologous chromosomes. This 5'-3' end-resection of the DNA duplex is an essential process, conserved across all three domains of life: the bacteria, eukaryota and archaea. In the present review, we examine the numerous and redundant helicase and nuclease systems that function as the enzymatic analogues for this crucial process in the three major phylogenetic divisions.

AB - During DNA repair by HR (homologous recombination), the ends of a DNA DSB (double-strand break) must be resected to generate single-stranded tails, which are required for strand invasion and exchange with homologous chromosomes. This 5'-3' end-resection of the DNA duplex is an essential process, conserved across all three domains of life: the bacteria, eukaryota and archaea. In the present review, we examine the numerous and redundant helicase and nuclease systems that function as the enzymatic analogues for this crucial process in the three major phylogenetic divisions.

KW - DNA

KW - DNA Damage

KW - DNA, Archaeal

KW - DNA, Bacterial

KW - Eukaryotic Cells

KW - Phylogeny

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.1042/BST20120307

DO - 10.1042/BST20120307

M3 - Journal article

C2 - 23356304

VL - 41

SP - 314

EP - 320

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

SN - 0300-5127

IS - 1

ER -