Home > Research > Publications & Outputs > Enhancing epidemiological surveillance of the e...


Text available via DOI:

View graph of relations

Enhancing epidemiological surveillance of the emergence of the SARS-CoV-2 Omicron variant using spike gene target failure data, England, 15 November to 31 December 2021

Research output: Contribution to Journal/MagazineJournal articlepeer-review

  • Paula B Blomquist
  • Neil Bray
  • Anne Marie O’Connell
  • Daniel West
  • Natalie Groves
  • Eileen Gallagher
  • Lara Utsi
  • Christopher I Jarvis
  • Jo L Hardstaff
  • Chloe Byers
  • Soeren Metelmann
  • David Simons
  • Asad Zaidi
  • Katherine A Twohig
  • Bethan Savagar
  • Alessandra Løchen
  • Katie Wrenn
  • María Saavedra-Campos
  • Zahidul Abedin
  • Isaac Florence
  • Paul Cleary
  • Richard Elson
  • Roberto Vivancos
  • Iain R Lake
Article number2200143
<mark>Journal publication date</mark>17/03/2022
Issue number11
Number of pages5
Publication StatusPublished
<mark>Original language</mark>English


When SARS-CoV-2 Omicron emerged in 2021, S gene target failure enabled differentiation between Omicron and the dominant Delta variant. In England, where S gene target surveillance (SGTS) was already established, this led to rapid identification (within ca 3 days of sample collection) of possible Omicron cases, alongside real-time surveillance and modelling of Omicron growth. SGTS was key to public health action (including case identification and incident management), and we share applied insights on how and when to use SGTS.