Home > Research > Publications & Outputs > Estimation of Spatial Variation in Risk Using M...
View graph of relations

Estimation of Spatial Variation in Risk Using Matched Case-control Data.

Research output: Contribution to Journal/MagazineJournal article

Published

Standard

Estimation of Spatial Variation in Risk Using Matched Case-control Data. / Jarner, Mikala F.; Diggle, Peter J.; Chetwynd, Amanda G.
In: Biometrical Journal, Vol. 44, No. 8, 12.2002, p. 936-945.

Research output: Contribution to Journal/MagazineJournal article

Harvard

APA

Vancouver

Jarner MF, Diggle PJ, Chetwynd AG. Estimation of Spatial Variation in Risk Using Matched Case-control Data. Biometrical Journal. 2002 Dec;44(8):936-945. doi: 10.1002/bimj.200290005

Author

Jarner, Mikala F. ; Diggle, Peter J. ; Chetwynd, Amanda G. / Estimation of Spatial Variation in Risk Using Matched Case-control Data. In: Biometrical Journal. 2002 ; Vol. 44, No. 8. pp. 936-945.

Bibtex

@article{c7b02a6b37ff485aa9998880b03b5b4d,
title = "Estimation of Spatial Variation in Risk Using Matched Case-control Data.",
abstract = "A common problem in environmental epidemiology is to estimate spatial variation in disease risk after accounting for known risk factors. In this paper we consider this problem in the context of matched case-control studies. We extend the generalised additive model approach of Kelsall and Diggle (1998) to studies in which each case has been individually matched to a set of controls. We discuss a method for fitting this model to data, apply the method to a matched study on perinatal death in the North West Thames region of England and explain why, if spatial variation is of particular scientific interest, matching is undesirable.",
keywords = "Spatial variation in risk • Generalised additive models • Epidemiology • Matched case-control design",
author = "Jarner, {Mikala F.} and Diggle, {Peter J.} and Chetwynd, {Amanda G.}",
year = "2002",
month = dec,
doi = "10.1002/bimj.200290005",
language = "English",
volume = "44",
pages = "936--945",
journal = "Biometrical Journal",
issn = "1521-4036",
publisher = "Wiley-VCH Verlag",
number = "8",

}

RIS

TY - JOUR

T1 - Estimation of Spatial Variation in Risk Using Matched Case-control Data.

AU - Jarner, Mikala F.

AU - Diggle, Peter J.

AU - Chetwynd, Amanda G.

PY - 2002/12

Y1 - 2002/12

N2 - A common problem in environmental epidemiology is to estimate spatial variation in disease risk after accounting for known risk factors. In this paper we consider this problem in the context of matched case-control studies. We extend the generalised additive model approach of Kelsall and Diggle (1998) to studies in which each case has been individually matched to a set of controls. We discuss a method for fitting this model to data, apply the method to a matched study on perinatal death in the North West Thames region of England and explain why, if spatial variation is of particular scientific interest, matching is undesirable.

AB - A common problem in environmental epidemiology is to estimate spatial variation in disease risk after accounting for known risk factors. In this paper we consider this problem in the context of matched case-control studies. We extend the generalised additive model approach of Kelsall and Diggle (1998) to studies in which each case has been individually matched to a set of controls. We discuss a method for fitting this model to data, apply the method to a matched study on perinatal death in the North West Thames region of England and explain why, if spatial variation is of particular scientific interest, matching is undesirable.

KW - Spatial variation in risk • Generalised additive models • Epidemiology • Matched case-control design

U2 - 10.1002/bimj.200290005

DO - 10.1002/bimj.200290005

M3 - Journal article

VL - 44

SP - 936

EP - 945

JO - Biometrical Journal

JF - Biometrical Journal

SN - 1521-4036

IS - 8

ER -