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Ethical challenges of radical innovation in assisted reproduction

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Ethical challenges of radical innovation in assisted reproduction. / Appleby, John.
Multicultural & Interreligious Perspectives on the Ethics of Human Reproduction - Protecting Future Generations. ed. / Joseph Tham; Alberto Garcia Gómez; John Lunstroth. Cham: Springer, 2022. p. 1-12 (Religion and Human Rights; Vol. 9).

Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter (peer-reviewed) › peer-review

Harvard

Appleby, J 2022, Ethical challenges of radical innovation in assisted reproduction. in J Tham, A Garcia Gómez & J Lunstroth (eds), Multicultural & Interreligious Perspectives on the Ethics of Human Reproduction - Protecting Future Generations. Religion and Human Rights, vol. 9, Springer, Cham, pp. 1-12. https://doi.org/10.1007/978-3-030-86938-0_1

APA

Appleby, J. (2022). Ethical challenges of radical innovation in assisted reproduction. In J. Tham, A. Garcia Gómez, & J. Lunstroth (Eds.), Multicultural & Interreligious Perspectives on the Ethics of Human Reproduction - Protecting Future Generations (pp. 1-12). (Religion and Human Rights; Vol. 9). Springer. https://doi.org/10.1007/978-3-030-86938-0_1

Vancouver

Appleby J. Ethical challenges of radical innovation in assisted reproduction. In Tham J, Garcia Gómez A, Lunstroth J, editors, Multicultural & Interreligious Perspectives on the Ethics of Human Reproduction - Protecting Future Generations. Cham: Springer. 2022. p. 1-12. (Religion and Human Rights). doi: 10.1007/978-3-030-86938-0_1

Author

Appleby, John. / Ethical challenges of radical innovation in assisted reproduction. Multicultural & Interreligious Perspectives on the Ethics of Human Reproduction - Protecting Future Generations. editor / Joseph Tham ; Alberto Garcia Gómez ; John Lunstroth. Cham : Springer, 2022. pp. 1-12 (Religion and Human Rights).

Bibtex

@inbook{4bc4fd1b09ae4fc9a2ce93596f8a646d,
title = "Ethical challenges of radical innovation in assisted reproduction",
abstract = "In this chapter I ask the following question: what are some of the key ethical challenges presented by radical innovations in assisted reproduction and, when possible, how should these challenges be addressed? My response to this question aims to take into account Article 16 (Protecting future generations) of the UNESCO Declaration on Bioethics and Human Rights. While the number of ethical challenges that emerge with the radical innovation of reproductive technologies are too numerous to address in one piece of work, I aim to address a set of four critical areas of concern in this chapter. First, I make some terminological clarifications surrounding the use of the term {\textquoteleft}radical innovation{\textquoteright} in assisted reproduction. Second, I argue that the emergence of radical innovations in assisted reproduction requires that we take a more nuanced approach to use the word {\textquoteleft}parent{\textquoteright} to ensure that future ethical debates and regulations are precise and meaningful. This is crucial if the aim is to develop effective ethics and regulations to protect future generations. Third, I argue that radical innovations in assisted reproduction, such as in-vitro derived gametes, have disrupted our traditional concepts of {\textquoteleft}genetic relatedness{\textquoteright} and our perception of future offspring{\textquoteright}s genetic constitution. Fourth, I argue that radical innovation in assisted reproduction presents society with a range of safety risks and costs, but also the promise of ultimately making reproduction safer. However, I argue that society has a responsibility to ensure that the introduction of radical innovations is translated from bench to bedside with the aim of prioritizing the safety and welfare of future generations (and their parents) and fostering trust in science.",
keywords = "Innovation, Assisted reproduction, Mitochondrial replacement, ectogenesis, In-vitro derived gametes, CRISPR, Gene editing, Genetic relatedness",
author = "John Appleby",
year = "2022",
month = jan,
day = "3",
doi = "10.1007/978-3-030-86938-0_1",
language = "English",
isbn = "9783030869373",
series = "Religion and Human Rights",
publisher = "Springer",
pages = "1--12",
editor = "Joseph Tham and {Garcia G{\'o}mez}, Alberto and John Lunstroth",
booktitle = "Multicultural & Interreligious Perspectives on the Ethics of Human Reproduction - Protecting Future Generations",

}

RIS

TY - CHAP

T1 - Ethical challenges of radical innovation in assisted reproduction

AU - Appleby, John

PY - 2022/1/3

Y1 - 2022/1/3

N2 - In this chapter I ask the following question: what are some of the key ethical challenges presented by radical innovations in assisted reproduction and, when possible, how should these challenges be addressed? My response to this question aims to take into account Article 16 (Protecting future generations) of the UNESCO Declaration on Bioethics and Human Rights. While the number of ethical challenges that emerge with the radical innovation of reproductive technologies are too numerous to address in one piece of work, I aim to address a set of four critical areas of concern in this chapter. First, I make some terminological clarifications surrounding the use of the term ‘radical innovation’ in assisted reproduction. Second, I argue that the emergence of radical innovations in assisted reproduction requires that we take a more nuanced approach to use the word ‘parent’ to ensure that future ethical debates and regulations are precise and meaningful. This is crucial if the aim is to develop effective ethics and regulations to protect future generations. Third, I argue that radical innovations in assisted reproduction, such as in-vitro derived gametes, have disrupted our traditional concepts of ‘genetic relatedness’ and our perception of future offspring’s genetic constitution. Fourth, I argue that radical innovation in assisted reproduction presents society with a range of safety risks and costs, but also the promise of ultimately making reproduction safer. However, I argue that society has a responsibility to ensure that the introduction of radical innovations is translated from bench to bedside with the aim of prioritizing the safety and welfare of future generations (and their parents) and fostering trust in science.

AB - In this chapter I ask the following question: what are some of the key ethical challenges presented by radical innovations in assisted reproduction and, when possible, how should these challenges be addressed? My response to this question aims to take into account Article 16 (Protecting future generations) of the UNESCO Declaration on Bioethics and Human Rights. While the number of ethical challenges that emerge with the radical innovation of reproductive technologies are too numerous to address in one piece of work, I aim to address a set of four critical areas of concern in this chapter. First, I make some terminological clarifications surrounding the use of the term ‘radical innovation’ in assisted reproduction. Second, I argue that the emergence of radical innovations in assisted reproduction requires that we take a more nuanced approach to use the word ‘parent’ to ensure that future ethical debates and regulations are precise and meaningful. This is crucial if the aim is to develop effective ethics and regulations to protect future generations. Third, I argue that radical innovations in assisted reproduction, such as in-vitro derived gametes, have disrupted our traditional concepts of ‘genetic relatedness’ and our perception of future offspring’s genetic constitution. Fourth, I argue that radical innovation in assisted reproduction presents society with a range of safety risks and costs, but also the promise of ultimately making reproduction safer. However, I argue that society has a responsibility to ensure that the introduction of radical innovations is translated from bench to bedside with the aim of prioritizing the safety and welfare of future generations (and their parents) and fostering trust in science.

KW - Innovation

KW - Assisted reproduction

KW - Mitochondrial replacement

KW - ectogenesis

KW - In-vitro derived gametes

KW - CRISPR

KW - Gene editing

KW - Genetic relatedness

U2 - 10.1007/978-3-030-86938-0_1

DO - 10.1007/978-3-030-86938-0_1

M3 - Chapter (peer-reviewed)

SN - 9783030869373

T3 - Religion and Human Rights

SP - 1

EP - 12

BT - Multicultural & Interreligious Perspectives on the Ethics of Human Reproduction - Protecting Future Generations

A2 - Tham, Joseph

A2 - Garcia Gómez, Alberto

A2 - Lunstroth, John

PB - Springer

CY - Cham

ER -