In anticipation of the Euclid Wide and Deep Surveys, we present optical emission-line predictions at intermediate redshifts from 0.4 to 2.5. Our approach combines a mock light cone from the GAEA semi-analytic model to self-consistently model nebular emission from HII regions, narrow-line regions of active galactic nuclei (AGN), and evolved stellar populations. Our analysis focuses on seven optical emission lines: H$\alpha$, H$\beta$, [SII]$\lambda\lambda 6717, 6731$, [NII]$\lambda 6584$, [OI]$\lambda 6300$, [OIII]$\lambda 5007$, and [OII]$\lambda\lambda 3727, 3729$. We find that Euclid will predominantly observe massive, star-forming, and metal-rich line-emitters. Interstellar dust, modelled using a Calzetti law with mass-dependent scaling, may decrease observable percentages by a further 20-30% with respect to our underlying emission-line populations from GAEA. We predict Euclid to observe around 30-70% of H$\alpha$-, [NII]-, [SII]-, and [OIII]-emitting galaxies at redshift below 1 and under 10% at higher redshift. Observability of H$\beta$-, [OII]-, and [OI]- emission is limited to below 5%. For the Euclid-observable sample, we find that BPT diagrams can effectively distinguish between different galaxy types up to around redshift 1.8, attributed to the bias toward metal-rich systems. Moreover, we show that the relationships of H$\alpha$ and [OIII]+H$\beta$ to the star-formation rate, and the [OIII]-AGN luminosity relation, exhibit minimal changes with increasing redshift. Based on line ratios [NII]/H$\alpha$, [NII]/[OII], and [NII]/[SII], we further propose novel z-invariant tracers for the black hole accretion rate-to-star formation rate ratio. Lastly, we find that commonly used metallicity estimators display gradual shifts in normalisations with increasing redshift, while maintaining the overall shape of local calibrations. This is in tentative agreement with recent JWST data.