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    Rights statement: This is the author’s version of a work that was accepted for publication in Journal of the American Academy of Child and Adolescent Psychiatry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of the American Academy of Child and Adolescent Psychiatry, 55, 11 2016 DOI: 10.1016/j.jaac.2016.07.774

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Functional adult outcomes 16 years after childhood diagnosis of Attention-Deficit/Hyperactivity Disorder: MTA results

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Functional adult outcomes 16 years after childhood diagnosis of Attention-Deficit/Hyperactivity Disorder : MTA results . / MTA Cooperative Group.

In: Journal of the Amercian Academy of Child and Adolescent Psychiatry, Vol. 55, No. 11, 11.2016, p. 945-952.e2.

Research output: Contribution to journalJournal articlepeer-review

Harvard

MTA Cooperative Group 2016, 'Functional adult outcomes 16 years after childhood diagnosis of Attention-Deficit/Hyperactivity Disorder: MTA results ', Journal of the Amercian Academy of Child and Adolescent Psychiatry, vol. 55, no. 11, pp. 945-952.e2. https://doi.org/10.1016/j.jaac.2016.07.774

APA

MTA Cooperative Group (2016). Functional adult outcomes 16 years after childhood diagnosis of Attention-Deficit/Hyperactivity Disorder: MTA results . Journal of the Amercian Academy of Child and Adolescent Psychiatry, 55(11), 945-952.e2. https://doi.org/10.1016/j.jaac.2016.07.774

Vancouver

MTA Cooperative Group. Functional adult outcomes 16 years after childhood diagnosis of Attention-Deficit/Hyperactivity Disorder: MTA results . Journal of the Amercian Academy of Child and Adolescent Psychiatry. 2016 Nov;55(11):945-952.e2. https://doi.org/10.1016/j.jaac.2016.07.774

Author

MTA Cooperative Group. / Functional adult outcomes 16 years after childhood diagnosis of Attention-Deficit/Hyperactivity Disorder : MTA results . In: Journal of the Amercian Academy of Child and Adolescent Psychiatry. 2016 ; Vol. 55, No. 11. pp. 945-952.e2.

Bibtex

@article{bf4c2843280b431fb5460cd704f27b35,
title = "Functional adult outcomes 16 years after childhood diagnosis of Attention-Deficit/Hyperactivity Disorder: MTA results ",
abstract = "ObjectiveTo compare educational, occupational, legal, emotional, substance use disorder, and sexual-behavior outcomes in young adults with persistent and desistent attention-deficit/hyperactivity disorder (ADHD) symptoms and a local normative comparison group (LNCG) in the Multimodal Treatment Study of Children with ADHD (MTA).MethodData were collected 12, 14, and 16 years post-baseline (mean age 24.7 years at 16 years post-baseline) from 476 participants with ADHD diagnosed at age 7-9, and 241 age- and sex-matched classmates. Probands were subgrouped on persistence vs. desistence of DSM-5 symptom count. Orthogonal comparisons contrasted ADHD vs. LNCG and Symptom-Persistent (50%) vs. Symptom-Desistent (50%) subgroups. Functional outcomes were measured with standardized and demographic instruments.ResultsThree patterns of functional outcomes emerged. Post-secondary education, times fired/quit a job, current income, receiving public assistance, and risky sexual behavior showed the most common pattern: the LNCG fared best, Symptom-Persistent ADHD worst, and Symptom-Desistent ADHD between, with largest effect sizes between LNCG and Symptom-Persistent ADHD. In the second pattern, seen with emotional outcomes (emotional lability, neuroticism, anxiety disorder, mood disorder) and substance use outcomes, the LNCG and Symptom-Desistent ADHD did not differ, but both fared better than Symptom-Persistent ADHD. In the third pattern, noted with jail time (rare), alcohol use disorder (common), and number of jobs held, group differences were not significant. The ADHD group had 10 deaths compared to one in the LNCG.ConclusionAdult functioning after childhood ADHD varies by domain and is generally worse when ADHD symptoms persist. It is important to identify factors and interventions that promote better functional outcomes.",
keywords = "ADHD, adult outcomes, follow-up, MTA, functional outcomes",
author = "Lily Hechtman and Swanson, {James M.} and Sibley, {Margaret H.} and Annamarie Stehli and Owens, {Elizabeth B.} and Mitchell, {John T.} and Arnold, {L. Eugene} and Molina, {Brooke S. G.} and Hinshaw, {Stephen P.} and Jensen, {Peter S.} and Howard Abikoff and {Perez Algorta}, {Guillermo Daniel} and Howard, {Andrea L.} and Betsy Hoza and Joy Etcovitch and Sylviane Houssais and Lakes, {Kimberly D.} and Nichols, {J. Quyen} and {MTA Cooperative Group}",
note = "This is the author{\textquoteright}s version of a work that was accepted for publication in Journal of the American Academy of Child and Adolescent Psychiatry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of the American Academy of Child and Adolescent Psychiatry, 55, 11, 2016 DOI: 10.1016/j.jaac.2016.07.774",
year = "2016",
month = nov,
doi = "10.1016/j.jaac.2016.07.774",
language = "English",
volume = "55",
pages = "945--952.e2",
journal = "Journal of the Amercian Academy of Child and Adolescent Psychiatry",
issn = "0890-8567",
publisher = "Elsevier Limited",
number = "11",

}

RIS

TY - JOUR

T1 - Functional adult outcomes 16 years after childhood diagnosis of Attention-Deficit/Hyperactivity Disorder

T2 - MTA results

AU - Hechtman, Lily

AU - Swanson, James M.

AU - Sibley, Margaret H.

AU - Stehli, Annamarie

AU - Owens, Elizabeth B.

AU - Mitchell, John T.

AU - Arnold, L. Eugene

AU - Molina, Brooke S. G.

AU - Hinshaw, Stephen P.

AU - Jensen, Peter S.

AU - Abikoff, Howard

AU - Perez Algorta, Guillermo Daniel

AU - Howard, Andrea L.

AU - Hoza, Betsy

AU - Etcovitch, Joy

AU - Houssais, Sylviane

AU - Lakes, Kimberly D.

AU - Nichols, J. Quyen

AU - MTA Cooperative Group

N1 - This is the author’s version of a work that was accepted for publication in Journal of the American Academy of Child and Adolescent Psychiatry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of the American Academy of Child and Adolescent Psychiatry, 55, 11, 2016 DOI: 10.1016/j.jaac.2016.07.774

PY - 2016/11

Y1 - 2016/11

N2 - ObjectiveTo compare educational, occupational, legal, emotional, substance use disorder, and sexual-behavior outcomes in young adults with persistent and desistent attention-deficit/hyperactivity disorder (ADHD) symptoms and a local normative comparison group (LNCG) in the Multimodal Treatment Study of Children with ADHD (MTA).MethodData were collected 12, 14, and 16 years post-baseline (mean age 24.7 years at 16 years post-baseline) from 476 participants with ADHD diagnosed at age 7-9, and 241 age- and sex-matched classmates. Probands were subgrouped on persistence vs. desistence of DSM-5 symptom count. Orthogonal comparisons contrasted ADHD vs. LNCG and Symptom-Persistent (50%) vs. Symptom-Desistent (50%) subgroups. Functional outcomes were measured with standardized and demographic instruments.ResultsThree patterns of functional outcomes emerged. Post-secondary education, times fired/quit a job, current income, receiving public assistance, and risky sexual behavior showed the most common pattern: the LNCG fared best, Symptom-Persistent ADHD worst, and Symptom-Desistent ADHD between, with largest effect sizes between LNCG and Symptom-Persistent ADHD. In the second pattern, seen with emotional outcomes (emotional lability, neuroticism, anxiety disorder, mood disorder) and substance use outcomes, the LNCG and Symptom-Desistent ADHD did not differ, but both fared better than Symptom-Persistent ADHD. In the third pattern, noted with jail time (rare), alcohol use disorder (common), and number of jobs held, group differences were not significant. The ADHD group had 10 deaths compared to one in the LNCG.ConclusionAdult functioning after childhood ADHD varies by domain and is generally worse when ADHD symptoms persist. It is important to identify factors and interventions that promote better functional outcomes.

AB - ObjectiveTo compare educational, occupational, legal, emotional, substance use disorder, and sexual-behavior outcomes in young adults with persistent and desistent attention-deficit/hyperactivity disorder (ADHD) symptoms and a local normative comparison group (LNCG) in the Multimodal Treatment Study of Children with ADHD (MTA).MethodData were collected 12, 14, and 16 years post-baseline (mean age 24.7 years at 16 years post-baseline) from 476 participants with ADHD diagnosed at age 7-9, and 241 age- and sex-matched classmates. Probands were subgrouped on persistence vs. desistence of DSM-5 symptom count. Orthogonal comparisons contrasted ADHD vs. LNCG and Symptom-Persistent (50%) vs. Symptom-Desistent (50%) subgroups. Functional outcomes were measured with standardized and demographic instruments.ResultsThree patterns of functional outcomes emerged. Post-secondary education, times fired/quit a job, current income, receiving public assistance, and risky sexual behavior showed the most common pattern: the LNCG fared best, Symptom-Persistent ADHD worst, and Symptom-Desistent ADHD between, with largest effect sizes between LNCG and Symptom-Persistent ADHD. In the second pattern, seen with emotional outcomes (emotional lability, neuroticism, anxiety disorder, mood disorder) and substance use outcomes, the LNCG and Symptom-Desistent ADHD did not differ, but both fared better than Symptom-Persistent ADHD. In the third pattern, noted with jail time (rare), alcohol use disorder (common), and number of jobs held, group differences were not significant. The ADHD group had 10 deaths compared to one in the LNCG.ConclusionAdult functioning after childhood ADHD varies by domain and is generally worse when ADHD symptoms persist. It is important to identify factors and interventions that promote better functional outcomes.

KW - ADHD

KW - adult outcomes

KW - follow-up

KW - MTA

KW - functional outcomes

U2 - 10.1016/j.jaac.2016.07.774

DO - 10.1016/j.jaac.2016.07.774

M3 - Journal article

VL - 55

SP - 945-952.e2

JO - Journal of the Amercian Academy of Child and Adolescent Psychiatry

JF - Journal of the Amercian Academy of Child and Adolescent Psychiatry

SN - 0890-8567

IS - 11

ER -