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High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Published
  • Samuel Lawman
  • Yue Dong
  • Bryan M. Williams
  • Vito Romano
  • Stephen Kaye
  • Simon P. Harding
  • Colin Willoughby
  • Yao Chun Shen
  • Yalin Zheng
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<mark>Journal publication date</mark>30/05/2016
<mark>Journal</mark>Optics Express
Issue number11
Volume24
Number of pages11
Pages (from-to)12395-12405
Publication StatusPublished
<mark>Original language</mark>English

Abstract

We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using a broad bandwidth and spatial coherent Super-Continuum (SC) source. With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 μm in air and 3D volume imaging speeds up to 213 kA-Scan/s. Furthermore, we report the use of a single SC pulse, of 2 ns duration, to temporally gate an OCT B-Scan image of 70 A-Scans. This is the equivalent of 35 GA-Scans/s. We apply the CW setup for high resolution imaging of the fine structures of a human cornea sample ex-vivo. The single pulse setup is applied to imaging of a coated pharmaceutical tablet. The fixed pattern noise due to spectral noise is removed by subtracting the median magnitude A-Scan. We also demonstrate that the Fourier phase can be used to remove aberration caused artefacts.