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High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography. / Lawman, Samuel; Dong, Yue; Williams, Bryan M. et al.
In: Optics Express, Vol. 24, No. 11, 30.05.2016, p. 12395-12405.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Lawman, S, Dong, Y, Williams, BM, Romano, V, Kaye, S, Harding, SP, Willoughby, C, Shen, YC & Zheng, Y 2016, 'High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography', Optics Express, vol. 24, no. 11, pp. 12395-12405. https://doi.org/10.1364/OE.24.012395

APA

Lawman, S., Dong, Y., Williams, B. M., Romano, V., Kaye, S., Harding, S. P., Willoughby, C., Shen, Y. C., & Zheng, Y. (2016). High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography. Optics Express, 24(11), 12395-12405. https://doi.org/10.1364/OE.24.012395

Vancouver

Lawman S, Dong Y, Williams BM, Romano V, Kaye S, Harding SP et al. High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography. Optics Express. 2016 May 30;24(11):12395-12405. doi: 10.1364/OE.24.012395

Author

Lawman, Samuel ; Dong, Yue ; Williams, Bryan M. et al. / High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography. In: Optics Express. 2016 ; Vol. 24, No. 11. pp. 12395-12405.

Bibtex

@article{08739efeb75d4f5ca8f0901e009e5cb6,
title = "High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography",
abstract = "We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using a broad bandwidth and spatial coherent Super-Continuum (SC) source. With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 μm in air and 3D volume imaging speeds up to 213 kA-Scan/s. Furthermore, we report the use of a single SC pulse, of 2 ns duration, to temporally gate an OCT B-Scan image of 70 A-Scans. This is the equivalent of 35 GA-Scans/s. We apply the CW setup for high resolution imaging of the fine structures of a human cornea sample ex-vivo. The single pulse setup is applied to imaging of a coated pharmaceutical tablet. The fixed pattern noise due to spectral noise is removed by subtracting the median magnitude A-Scan. We also demonstrate that the Fourier phase can be used to remove aberration caused artefacts.",
author = "Samuel Lawman and Yue Dong and Williams, {Bryan M.} and Vito Romano and Stephen Kaye and Harding, {Simon P.} and Colin Willoughby and Shen, {Yao Chun} and Yalin Zheng",
year = "2016",
month = may,
day = "30",
doi = "10.1364/OE.24.012395",
language = "English",
volume = "24",
pages = "12395--12405",
journal = "Optics Express",
issn = "1094-4087",
publisher = "Optical Society of American (OSA)",
number = "11",

}

RIS

TY - JOUR

T1 - High resolution corneal and single pulse imaging with line field spectral domain optical coherence tomography

AU - Lawman, Samuel

AU - Dong, Yue

AU - Williams, Bryan M.

AU - Romano, Vito

AU - Kaye, Stephen

AU - Harding, Simon P.

AU - Willoughby, Colin

AU - Shen, Yao Chun

AU - Zheng, Yalin

PY - 2016/5/30

Y1 - 2016/5/30

N2 - We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using a broad bandwidth and spatial coherent Super-Continuum (SC) source. With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 μm in air and 3D volume imaging speeds up to 213 kA-Scan/s. Furthermore, we report the use of a single SC pulse, of 2 ns duration, to temporally gate an OCT B-Scan image of 70 A-Scans. This is the equivalent of 35 GA-Scans/s. We apply the CW setup for high resolution imaging of the fine structures of a human cornea sample ex-vivo. The single pulse setup is applied to imaging of a coated pharmaceutical tablet. The fixed pattern noise due to spectral noise is removed by subtracting the median magnitude A-Scan. We also demonstrate that the Fourier phase can be used to remove aberration caused artefacts.

AB - We report the development of a Spectral Domain Line Field Optical Coherence Tomography (LF-OCT) system, using a broad bandwidth and spatial coherent Super-Continuum (SC) source. With conventional quasi-Continuous Wave (CW) setup we achieve axial resolutions up to 2.1 μm in air and 3D volume imaging speeds up to 213 kA-Scan/s. Furthermore, we report the use of a single SC pulse, of 2 ns duration, to temporally gate an OCT B-Scan image of 70 A-Scans. This is the equivalent of 35 GA-Scans/s. We apply the CW setup for high resolution imaging of the fine structures of a human cornea sample ex-vivo. The single pulse setup is applied to imaging of a coated pharmaceutical tablet. The fixed pattern noise due to spectral noise is removed by subtracting the median magnitude A-Scan. We also demonstrate that the Fourier phase can be used to remove aberration caused artefacts.

U2 - 10.1364/OE.24.012395

DO - 10.1364/OE.24.012395

M3 - Journal article

AN - SCOPUS:84973601396

VL - 24

SP - 12395

EP - 12405

JO - Optics Express

JF - Optics Express

SN - 1094-4087

IS - 11

ER -