Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter
Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSN › Chapter
}
TY - CHAP
T1 - Host-parasite interactions and the evolution of immune defense
AU - Wilson, Kenneth
AU - Cotter, Sheena C.
PY - 2013
Y1 - 2013
N2 - Opening paragraph: Parasites are both numerous and ubiquitous, and so all living organisms face a continual struggle to fend off a constant barrage of immunological insults within their environment. The mechanisms for doing so are many and varied; they include physical and chemical defenses, such as thick skin, fur, or cuticle; behavioral defenses, such as grooming, behavioral fever, and self-medication; and immune defenses, including the innate immune systemcommon to all animals and the vertebrate-specific acquired immune system (Schmid-Hempel, 2011; Wilson, 2005). Since the advent of molecular advances such as whole-genome sequencing and next-generation techniques, our mechanistic understanding of immune defenses has grown considerably for both vertebrates and invertebrates. Amongst the many things these have revealed is the similarity between many aspects of innate immune defences of vertebrates and invertebrates (Vilmos & Kurucz, 1998), and this has highlighted the utility of using insects, especially Drosophila, as model hosts for understanding the evolution of, and plasticity in, the innate immune response.
AB - Opening paragraph: Parasites are both numerous and ubiquitous, and so all living organisms face a continual struggle to fend off a constant barrage of immunological insults within their environment. The mechanisms for doing so are many and varied; they include physical and chemical defenses, such as thick skin, fur, or cuticle; behavioral defenses, such as grooming, behavioral fever, and self-medication; and immune defenses, including the innate immune systemcommon to all animals and the vertebrate-specific acquired immune system (Schmid-Hempel, 2011; Wilson, 2005). Since the advent of molecular advances such as whole-genome sequencing and next-generation techniques, our mechanistic understanding of immune defenses has grown considerably for both vertebrates and invertebrates. Amongst the many things these have revealed is the similarity between many aspects of innate immune defences of vertebrates and invertebrates (Vilmos & Kurucz, 1998), and this has highlighted the utility of using insects, especially Drosophila, as model hosts for understanding the evolution of, and plasticity in, the innate immune response.
KW - DENSITY-DEPENDENT PROPHYLAXIS
KW - TERMITE ZOOTERMOPSIS-ANGUSTICOLLIS
KW - SEXUALLY-TRANSMITTED-DISEASE
KW - SEPARATA WALKER LEPIDOPTERA
KW - PANORPA-VULGARIS HEMOCYTES
KW - NUCLEAR POLYHEDROSIS-VIRUS
KW - ILLNESS-INDUCED ANOREXIA
KW - MALE-BIASED PARASITISM
KW - LYSOZYME-LIKE ACTIVITY
KW - HISTORY TRADE-OFFS
U2 - 10.1016/B978-0-12-407186-5.00003-3
DO - 10.1016/B978-0-12-407186-5.00003-3
M3 - Chapter
SN - 978-0-12-407186-5
VL - 45
T3 - Advances in the Study of Behavior
SP - 81
EP - 174
BT - Advances in the study of behavior
A2 - Brockmann, H. Jane
A2 - Roper, Timothy J.
A2 - Naguib, Marc
A2 - Mitani, John C.
A2 - Simmons, Leigh W.
A2 - Barrett, Louise
PB - ELSEVIER ACADEMIC PRESS INC
CY - Amsterdam
ER -