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How can mathematics be used to improve burn care?

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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How can mathematics be used to improve burn care? / Egberts, Ginger; Vermolen, Fred; Peng, Qiyao et al.
In: Burns Open, Vol. 9, 100390, 31.01.2025.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Egberts, G, Vermolen, F, Peng, Q, Korkmaz, HI & van Zuijlen, P 2025, 'How can mathematics be used to improve burn care?', Burns Open, vol. 9, 100390. https://doi.org/10.1016/j.burnso.2024.100390

APA

Egberts, G., Vermolen, F., Peng, Q., Korkmaz, H. I., & van Zuijlen, P. (2025). How can mathematics be used to improve burn care? Burns Open, 9, Article 100390. https://doi.org/10.1016/j.burnso.2024.100390

Vancouver

Egberts G, Vermolen F, Peng Q, Korkmaz HI, van Zuijlen P. How can mathematics be used to improve burn care? Burns Open. 2025 Jan 31;9:100390. Epub 2025 Jan 3. doi: 10.1016/j.burnso.2024.100390

Author

Egberts, Ginger ; Vermolen, Fred ; Peng, Qiyao et al. / How can mathematics be used to improve burn care?. In: Burns Open. 2025 ; Vol. 9.

Bibtex

@article{9d1f916183b8464aa633a89a5d5dcb8c,
title = "How can mathematics be used to improve burn care?",
abstract = "Severe second-degree {\textquoteleft}partial thickness{\textquoteright} and third-degree {\textquoteleft}full thickness{\textquoteright} burns are characterized by damage to the dermal layer of the skin. In the dermis, specialized cells called fibroblasts play a crucial role in wound healing. These cells produce collagen, a protein that provides strength and structure to the skin. After burn injury, fibroblasts migrate to the injured area and start producing and depositing collagen to help repair the damaged tissue. While contraction is essential for closing the wound, it can also result in scar contraction (contractures), especially in more severe burns. This contraction creates stresses on the skin, which can deteriorate the mobility of joints near the burn. This article overviews the most recent research results in computer simulations of scar contraction after burns.",
keywords = "Agent-based models, Artificial intelligence, Continuum models, Mathematical models, Mathematics in the clinic, Parameter uncertainty, Post-burn contraction",
author = "Ginger Egberts and Fred Vermolen and Qiyao Peng and H.Ibrahim Korkmaz and {van Zuijlen}, Paul",
year = "2025",
month = jan,
day = "31",
doi = "10.1016/j.burnso.2024.100390",
language = "English",
volume = "9",
journal = "Burns Open",

}

RIS

TY - JOUR

T1 - How can mathematics be used to improve burn care?

AU - Egberts, Ginger

AU - Vermolen, Fred

AU - Peng, Qiyao

AU - Korkmaz, H.Ibrahim

AU - van Zuijlen, Paul

PY - 2025/1/31

Y1 - 2025/1/31

N2 - Severe second-degree ‘partial thickness’ and third-degree ‘full thickness’ burns are characterized by damage to the dermal layer of the skin. In the dermis, specialized cells called fibroblasts play a crucial role in wound healing. These cells produce collagen, a protein that provides strength and structure to the skin. After burn injury, fibroblasts migrate to the injured area and start producing and depositing collagen to help repair the damaged tissue. While contraction is essential for closing the wound, it can also result in scar contraction (contractures), especially in more severe burns. This contraction creates stresses on the skin, which can deteriorate the mobility of joints near the burn. This article overviews the most recent research results in computer simulations of scar contraction after burns.

AB - Severe second-degree ‘partial thickness’ and third-degree ‘full thickness’ burns are characterized by damage to the dermal layer of the skin. In the dermis, specialized cells called fibroblasts play a crucial role in wound healing. These cells produce collagen, a protein that provides strength and structure to the skin. After burn injury, fibroblasts migrate to the injured area and start producing and depositing collagen to help repair the damaged tissue. While contraction is essential for closing the wound, it can also result in scar contraction (contractures), especially in more severe burns. This contraction creates stresses on the skin, which can deteriorate the mobility of joints near the burn. This article overviews the most recent research results in computer simulations of scar contraction after burns.

KW - Agent-based models

KW - Artificial intelligence

KW - Continuum models

KW - Mathematical models

KW - Mathematics in the clinic

KW - Parameter uncertainty

KW - Post-burn contraction

U2 - 10.1016/j.burnso.2024.100390

DO - 10.1016/j.burnso.2024.100390

M3 - Journal article

VL - 9

JO - Burns Open

JF - Burns Open

M1 - 100390

ER -