Home > Research > Publications & Outputs > Interaction of infectious bursal disease virus ...
View graph of relations

Interaction of infectious bursal disease virus with the immune system of poultry

Research output: Contribution to journalReview articlepeer-review

Published

Standard

Interaction of infectious bursal disease virus with the immune system of poultry. / Rehman, Z. U.; Meng, C.; Umar, S.; Munir, M.; Ding, C.

In: World's Poultry Science Journal, Vol. 72, No. 4, 01.12.2016, p. 805-820.

Research output: Contribution to journalReview articlepeer-review

Harvard

Rehman, ZU, Meng, C, Umar, S, Munir, M & Ding, C 2016, 'Interaction of infectious bursal disease virus with the immune system of poultry', World's Poultry Science Journal, vol. 72, no. 4, pp. 805-820. https://doi.org/10.1017/S0043933916000775

APA

Rehman, Z. U., Meng, C., Umar, S., Munir, M., & Ding, C. (2016). Interaction of infectious bursal disease virus with the immune system of poultry. World's Poultry Science Journal, 72(4), 805-820. https://doi.org/10.1017/S0043933916000775

Vancouver

Rehman ZU, Meng C, Umar S, Munir M, Ding C. Interaction of infectious bursal disease virus with the immune system of poultry. World's Poultry Science Journal. 2016 Dec 1;72(4):805-820. https://doi.org/10.1017/S0043933916000775

Author

Rehman, Z. U. ; Meng, C. ; Umar, S. ; Munir, M. ; Ding, C. / Interaction of infectious bursal disease virus with the immune system of poultry. In: World's Poultry Science Journal. 2016 ; Vol. 72, No. 4. pp. 805-820.

Bibtex

@article{3e9ba3c67ec842318248933d12bb1794,
title = "Interaction of infectious bursal disease virus with the immune system of poultry",
abstract = "Immune dysfunction can be either at the humoral or cellular levels and is mediated by a myriad of factors including virus-induced immunosuppression. Infectious bursal disease virus (IBDV) affects domesticated poultry and causing health problems mainly due to prolonged immunosuppression. Destruction of the immunoglobulin-producing cells is the principal cause of IBDV-induced immunosuppression, which leads to significant impairment of the primary antibody responses. Due to these effects, IBDV infection not only increases the susceptibility of poultry to other viral infections but predisposes the host to several other bacteria of variable pathologies. The IBDV-induced immune-suppression is well-known phenomenon, however, recently there have been significant advancements in understanding the molecular mechanisms of this immune-suppression. This review discuss current updates regarding the immunotoxic and immunosuppressive nature of IBDV in the poultry and highlights areas requiring future research attentions that may help to establish foundations for effective and improved vaccines against IBDV.",
keywords = "immune cells, immunity, immunosuppression, infectious bursal disease virus, poultry",
author = "Rehman, {Z. U.} and C. Meng and S. Umar and M. Munir and C. Ding",
year = "2016",
month = dec,
day = "1",
doi = "10.1017/S0043933916000775",
language = "English",
volume = "72",
pages = "805--820",
journal = "World's Poultry Science Journal",
issn = "0043-9339",
publisher = "Cambridge University Press",
number = "4",

}

RIS

TY - JOUR

T1 - Interaction of infectious bursal disease virus with the immune system of poultry

AU - Rehman, Z. U.

AU - Meng, C.

AU - Umar, S.

AU - Munir, M.

AU - Ding, C.

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Immune dysfunction can be either at the humoral or cellular levels and is mediated by a myriad of factors including virus-induced immunosuppression. Infectious bursal disease virus (IBDV) affects domesticated poultry and causing health problems mainly due to prolonged immunosuppression. Destruction of the immunoglobulin-producing cells is the principal cause of IBDV-induced immunosuppression, which leads to significant impairment of the primary antibody responses. Due to these effects, IBDV infection not only increases the susceptibility of poultry to other viral infections but predisposes the host to several other bacteria of variable pathologies. The IBDV-induced immune-suppression is well-known phenomenon, however, recently there have been significant advancements in understanding the molecular mechanisms of this immune-suppression. This review discuss current updates regarding the immunotoxic and immunosuppressive nature of IBDV in the poultry and highlights areas requiring future research attentions that may help to establish foundations for effective and improved vaccines against IBDV.

AB - Immune dysfunction can be either at the humoral or cellular levels and is mediated by a myriad of factors including virus-induced immunosuppression. Infectious bursal disease virus (IBDV) affects domesticated poultry and causing health problems mainly due to prolonged immunosuppression. Destruction of the immunoglobulin-producing cells is the principal cause of IBDV-induced immunosuppression, which leads to significant impairment of the primary antibody responses. Due to these effects, IBDV infection not only increases the susceptibility of poultry to other viral infections but predisposes the host to several other bacteria of variable pathologies. The IBDV-induced immune-suppression is well-known phenomenon, however, recently there have been significant advancements in understanding the molecular mechanisms of this immune-suppression. This review discuss current updates regarding the immunotoxic and immunosuppressive nature of IBDV in the poultry and highlights areas requiring future research attentions that may help to establish foundations for effective and improved vaccines against IBDV.

KW - immune cells

KW - immunity

KW - immunosuppression

KW - infectious bursal disease virus

KW - poultry

U2 - 10.1017/S0043933916000775

DO - 10.1017/S0043933916000775

M3 - Review article

AN - SCOPUS:84997343318

VL - 72

SP - 805

EP - 820

JO - World's Poultry Science Journal

JF - World's Poultry Science Journal

SN - 0043-9339

IS - 4

ER -