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Involvement of sympathetic nerve activity in skin blood flow oscillations in humans

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Involvement of sympathetic nerve activity in skin blood flow oscillations in humans. / Söderström , Torbjörn; Stefanovska, Aneta; Veber, Mitja ; Svensson, Henry.

In: Anerican Journal of Physiology - Heart and Circulatory Physiology, Vol. 284, No. 5, 05.2003, p. H1638-H1646.

Research output: Contribution to journalJournal articlepeer-review

Harvard

Söderström , T, Stefanovska, A, Veber, M & Svensson, H 2003, 'Involvement of sympathetic nerve activity in skin blood flow oscillations in humans', Anerican Journal of Physiology - Heart and Circulatory Physiology, vol. 284, no. 5, pp. H1638-H1646. https://doi.org/10.1152/ajpheart.00826.2000

APA

Söderström , T., Stefanovska, A., Veber, M., & Svensson, H. (2003). Involvement of sympathetic nerve activity in skin blood flow oscillations in humans. Anerican Journal of Physiology - Heart and Circulatory Physiology, 284(5), H1638-H1646. https://doi.org/10.1152/ajpheart.00826.2000

Vancouver

Söderström T, Stefanovska A, Veber M, Svensson H. Involvement of sympathetic nerve activity in skin blood flow oscillations in humans. Anerican Journal of Physiology - Heart and Circulatory Physiology. 2003 May;284(5):H1638-H1646. https://doi.org/10.1152/ajpheart.00826.2000

Author

Söderström , Torbjörn ; Stefanovska, Aneta ; Veber, Mitja ; Svensson, Henry. / Involvement of sympathetic nerve activity in skin blood flow oscillations in humans. In: Anerican Journal of Physiology - Heart and Circulatory Physiology. 2003 ; Vol. 284, No. 5. pp. H1638-H1646.

Bibtex

@article{3216fae78ccb44908b295b305ee8eb16,
title = "Involvement of sympathetic nerve activity in skin blood flow oscillations in humans",
abstract = "We have used the wavelet transform to evaluate the time-frequency content of laser-Doppler flowmetry (LDF) signals measured simultaneously on the surfaces of free microvascular flaps deprived of sympathetic nerve activity (SNA), and on adjacent intact skin, in humans. It was thereby possible to determine the frequency interval within which SNA manifests itself in peripheral blood flow oscillations. The frequency interval from 0.0095 to 2 Hz was examined and was divided into five subintervals: I, similar to0.01 Hz; II, similar to0.04 Hz; III, similar to0.1 Hz; IV, similar to0.3 Hz; and V, similar to1 Hz. The average value of the LDF signal in the time domain as well as the mean amplitude and total power in the interval from 0.0095 to 2 Hz and amplitude and power within each of the five subintervals were significantly lower for signals measured on the free flap (P <0.002). The normalized spectral amplitude and power in the free flap were significantly lower in only two intervals: I, from 0.0095 to 0.021 Hz; and II, from 0.021 to 0.052 Hz (P <0.05); thus indicating that SNA is manifested in at least one of these frequency intervals. Because interval I has recently been shown to be the result of vascular endothelial activity, we conclude that we have identified SNA as influencing blood flow oscillations in normal tissues with repetition times of 20-50 s or frequencies of 0.02-0.05 Hz.",
keywords = "SPECTRUM ANALYSIS, FREQUENCY, time-frequency analysis, WAVES, blood flow variability, CONSCIOUS RATS, wavelet transform, HEART-RATE, POWER SPECTRUM, autoregulation, microvascular free flaps, PRESSURE, NEURONS, SMOOTH-MUSCLE",
author = "Torbj{\"o}rn S{\"o}derstr{\"o}m and Aneta Stefanovska and Mitja Veber and Henry Svensson",
year = "2003",
month = may,
doi = "10.1152/ajpheart.00826.2000",
language = "English",
volume = "284",
pages = "H1638--H1646",
journal = "Anerican Journal of Physiology - Heart and Circulatory Physiology",
issn = "0363-6135",
publisher = "American Physiological Society",
number = "5",

}

RIS

TY - JOUR

T1 - Involvement of sympathetic nerve activity in skin blood flow oscillations in humans

AU - Söderström , Torbjörn

AU - Stefanovska, Aneta

AU - Veber, Mitja

AU - Svensson, Henry

PY - 2003/5

Y1 - 2003/5

N2 - We have used the wavelet transform to evaluate the time-frequency content of laser-Doppler flowmetry (LDF) signals measured simultaneously on the surfaces of free microvascular flaps deprived of sympathetic nerve activity (SNA), and on adjacent intact skin, in humans. It was thereby possible to determine the frequency interval within which SNA manifests itself in peripheral blood flow oscillations. The frequency interval from 0.0095 to 2 Hz was examined and was divided into five subintervals: I, similar to0.01 Hz; II, similar to0.04 Hz; III, similar to0.1 Hz; IV, similar to0.3 Hz; and V, similar to1 Hz. The average value of the LDF signal in the time domain as well as the mean amplitude and total power in the interval from 0.0095 to 2 Hz and amplitude and power within each of the five subintervals were significantly lower for signals measured on the free flap (P <0.002). The normalized spectral amplitude and power in the free flap were significantly lower in only two intervals: I, from 0.0095 to 0.021 Hz; and II, from 0.021 to 0.052 Hz (P <0.05); thus indicating that SNA is manifested in at least one of these frequency intervals. Because interval I has recently been shown to be the result of vascular endothelial activity, we conclude that we have identified SNA as influencing blood flow oscillations in normal tissues with repetition times of 20-50 s or frequencies of 0.02-0.05 Hz.

AB - We have used the wavelet transform to evaluate the time-frequency content of laser-Doppler flowmetry (LDF) signals measured simultaneously on the surfaces of free microvascular flaps deprived of sympathetic nerve activity (SNA), and on adjacent intact skin, in humans. It was thereby possible to determine the frequency interval within which SNA manifests itself in peripheral blood flow oscillations. The frequency interval from 0.0095 to 2 Hz was examined and was divided into five subintervals: I, similar to0.01 Hz; II, similar to0.04 Hz; III, similar to0.1 Hz; IV, similar to0.3 Hz; and V, similar to1 Hz. The average value of the LDF signal in the time domain as well as the mean amplitude and total power in the interval from 0.0095 to 2 Hz and amplitude and power within each of the five subintervals were significantly lower for signals measured on the free flap (P <0.002). The normalized spectral amplitude and power in the free flap were significantly lower in only two intervals: I, from 0.0095 to 0.021 Hz; and II, from 0.021 to 0.052 Hz (P <0.05); thus indicating that SNA is manifested in at least one of these frequency intervals. Because interval I has recently been shown to be the result of vascular endothelial activity, we conclude that we have identified SNA as influencing blood flow oscillations in normal tissues with repetition times of 20-50 s or frequencies of 0.02-0.05 Hz.

KW - SPECTRUM ANALYSIS

KW - FREQUENCY

KW - time-frequency analysis

KW - WAVES

KW - blood flow variability

KW - CONSCIOUS RATS

KW - wavelet transform

KW - HEART-RATE

KW - POWER SPECTRUM

KW - autoregulation

KW - microvascular free flaps

KW - PRESSURE

KW - NEURONS

KW - SMOOTH-MUSCLE

U2 - 10.1152/ajpheart.00826.2000

DO - 10.1152/ajpheart.00826.2000

M3 - Journal article

VL - 284

SP - H1638-H1646

JO - Anerican Journal of Physiology - Heart and Circulatory Physiology

JF - Anerican Journal of Physiology - Heart and Circulatory Physiology

SN - 0363-6135

IS - 5

ER -