Final published version
Licence: CC BY: Creative Commons Attribution 4.0 International License
Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Lifetime exercise is associated with eugonadism in aging men
T2 - a preliminary investigation
AU - Hayes, Lawrence D
AU - Sculthorpe, Nicholas
AU - Herbert, Peter
AU - Grace, Fergal
PY - 2017/6/1
Y1 - 2017/6/1
N2 - Testosterone is an important biological hormone, which displays a gradual decline with advancing age. Exercise training has been proposed as a first-line therapy for biochemical hypogonadism (clinically low serum testosterone). As such, the present investigation compared the incidence of biochemical hypogonadism (total testosterone <11.3 nmol·L-1) in a cohort of otherwise healthy lifelong sedentary men (SED [N=24], 63±5 years), compared with a positive control group of lifelong exercisers (LEX [N=16], 60±5 years) using electrochemiluminescent immunoassay. Fisher’s exact test identified significantly more of the SED group were classified as biochemically hypogonadal than the LEX group (8/24 compared to 2/16 respectively; p<.05). These data provide preliminary evidence that exercise may protect against the development of low testosterone defined hypogonadism in aging men.
AB - Testosterone is an important biological hormone, which displays a gradual decline with advancing age. Exercise training has been proposed as a first-line therapy for biochemical hypogonadism (clinically low serum testosterone). As such, the present investigation compared the incidence of biochemical hypogonadism (total testosterone <11.3 nmol·L-1) in a cohort of otherwise healthy lifelong sedentary men (SED [N=24], 63±5 years), compared with a positive control group of lifelong exercisers (LEX [N=16], 60±5 years) using electrochemiluminescent immunoassay. Fisher’s exact test identified significantly more of the SED group were classified as biochemically hypogonadal than the LEX group (8/24 compared to 2/16 respectively; p<.05). These data provide preliminary evidence that exercise may protect against the development of low testosterone defined hypogonadism in aging men.
M3 - Journal article
VL - 14
SP - 11
EP - 15
JO - Sport Scientific and Practical Aspects: International Scientific Journal of Kinesiology
JF - Sport Scientific and Practical Aspects: International Scientific Journal of Kinesiology
IS - 1
ER -