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Light-responsive biomaterials for ocular drug delivery

Research output: Contribution to Journal/MagazineLiterature reviewpeer-review

E-pub ahead of print
<mark>Journal publication date</mark>24/06/2022
<mark>Journal</mark>Drug Delivery and Translational Research
Number of pages24
Publication StatusE-pub ahead of print
Early online date24/06/22
<mark>Original language</mark>English

Abstract

Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems.