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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
}
TY - JOUR
T1 - Light-responsive biomaterials for ocular drug delivery
AU - Abdelmohsen, Hend
AU - Copeland, Nikki
AU - Hardy, John
PY - 2023/8/31
Y1 - 2023/8/31
N2 - Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems. Graphical abstract: [Figure not available: see fulltext.].
AB - Light-responsive biomaterials can be used for the delivery of therapeutic drugs and nucleic acids, where the tunable/precise delivery of payload highlights the potential of such biomaterials for treating a variety of conditions. The translucency of eyes and advances of laser technology in ophthalmology make light-responsive delivery of drugs feasible. Importantly, light can be applied in a non-invasive fashion; therefore, light-triggered drug delivery systems have great potential for clinical impact. This review will examine various types of light-responsive polymers and the chemistry that underpins their application as ophthalmic drug delivery systems. Graphical abstract: [Figure not available: see fulltext.].
KW - light-responsive
KW - Photochemistry
U2 - 10.1007/s13346-022-01196-5
DO - 10.1007/s13346-022-01196-5
M3 - Journal article
C2 - 35751001
VL - 13
SP - 2159
EP - 2182
JO - Drug Delivery and Translational Research
JF - Drug Delivery and Translational Research
SN - 2190-3948
IS - 8
ER -