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Final published version
Research output: Contribution to Journal/Magazine › Journal article › peer-review
| Article number | S74 |
|---|---|
| <mark>Journal publication date</mark> | 31/12/2003 |
| <mark>Journal</mark> | Genetics |
| Issue number | Suppl. 1 |
| Volume | 4 |
| Number of pages | 4 |
| Publication Status | Published |
| <mark>Original language</mark> | English |
This paper presents a method of performing model-free LOD-score based linkage analysis on quantitative traits. It is implemented in the QMFLINK program. The method is used to perform a genome screen on the Framingham Heart Study data. A number of markers that show some support for linkage in our study coincide substantially with those implicated in other linkage studies of hypertension. Although the new method needs further testing on additional real and simulated data sets we can already say that it is straightforward to apply and may offer a useful complementary approach to previously available methods for the linkage analysis of quantitative traits.