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Mast cells and innate immunity: Master troupes of the avian immune system

Research output: Contribution to Journal/Magazine › Review article › peer-review

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Mast cells and innate immunity: Master troupes of the avian immune system. / Rehman, Z. U.; Meng, C.; Umar, S. et al.
In: World's Poultry Science Journal, Vol. 73, No. 3, 09.2017, p. 621-632.

Research output: Contribution to Journal/Magazine › Review article › peer-review

Harvard

Rehman, ZU, Meng, C, Umar, S, Mahrose, KM, Ding, C & Munir, M 2017, 'Mast cells and innate immunity: Master troupes of the avian immune system', World's Poultry Science Journal, vol. 73, no. 3, pp. 621-632. https://doi.org/10.1017/S0043933917000526

APA

Rehman, Z. U., Meng, C., Umar, S., Mahrose, K. M., Ding, C., & Munir, M. (2017). Mast cells and innate immunity: Master troupes of the avian immune system. World's Poultry Science Journal, 73(3), 621-632. https://doi.org/10.1017/S0043933917000526

Vancouver

Rehman ZU, Meng C, Umar S, Mahrose KM, Ding C, Munir M. Mast cells and innate immunity: Master troupes of the avian immune system. World's Poultry Science Journal. 2017 Sept;73(3):621-632. Epub 2017 Aug 3. doi: 10.1017/S0043933917000526

Author

Rehman, Z. U. ; Meng, C. ; Umar, S. et al. / Mast cells and innate immunity : Master troupes of the avian immune system. In: World's Poultry Science Journal. 2017 ; Vol. 73, No. 3. pp. 621-632.

Bibtex

@article{b9edf6dc3eba4e9f89a5d2c22ac88435,
title = "Mast cells and innate immunity: Master troupes of the avian immune system",
abstract = "Mast cells (MCs) are granulated cells of haematopoietic lineage and constitute a major sensory arm of the immune system. MCs dually guard hosts and regulate immune responses against invading pathogens. This property of the MCs is attributed to their adaptability to detect stress signals and pathogens, and the production of signal specific mediators to engage immune cells for clearance of infectious agents. Pathogen-specific signals establish basis for the initiation of adoptive immune responses. These immune regulatory roles of MCs have opened avenues to engage different MCs activators which culminate in effective passive immunisation. The molecular mechanisms and dynamics of functionalities of MCs in host defences have been extensively characterised in mammals and rodents, and research on MCs in avian species is emerging. This review surveys the development, morphology and distribution of MCs in different tissues of the poultry and highlight areas that can be exploited for disease control and prevention.",
keywords = "Bacteria, Immune system, Mast cell, Parasite, Poultry, Virus",
author = "Rehman, {Z. U.} and C. Meng and S. Umar and Mahrose, {K. M.} and C. Ding and M. Munir",
year = "2017",
month = sep,
doi = "10.1017/S0043933917000526",
language = "English",
volume = "73",
pages = "621--632",
journal = "World's Poultry Science Journal",
issn = "0043-9339",
publisher = "Cambridge University Press",
number = "3",

}

RIS

TY - JOUR

T1 - Mast cells and innate immunity

T2 - Master troupes of the avian immune system

AU - Rehman, Z. U.

AU - Meng, C.

AU - Umar, S.

AU - Mahrose, K. M.

AU - Ding, C.

AU - Munir, M.

PY - 2017/9

Y1 - 2017/9

N2 - Mast cells (MCs) are granulated cells of haematopoietic lineage and constitute a major sensory arm of the immune system. MCs dually guard hosts and regulate immune responses against invading pathogens. This property of the MCs is attributed to their adaptability to detect stress signals and pathogens, and the production of signal specific mediators to engage immune cells for clearance of infectious agents. Pathogen-specific signals establish basis for the initiation of adoptive immune responses. These immune regulatory roles of MCs have opened avenues to engage different MCs activators which culminate in effective passive immunisation. The molecular mechanisms and dynamics of functionalities of MCs in host defences have been extensively characterised in mammals and rodents, and research on MCs in avian species is emerging. This review surveys the development, morphology and distribution of MCs in different tissues of the poultry and highlight areas that can be exploited for disease control and prevention.

AB - Mast cells (MCs) are granulated cells of haematopoietic lineage and constitute a major sensory arm of the immune system. MCs dually guard hosts and regulate immune responses against invading pathogens. This property of the MCs is attributed to their adaptability to detect stress signals and pathogens, and the production of signal specific mediators to engage immune cells for clearance of infectious agents. Pathogen-specific signals establish basis for the initiation of adoptive immune responses. These immune regulatory roles of MCs have opened avenues to engage different MCs activators which culminate in effective passive immunisation. The molecular mechanisms and dynamics of functionalities of MCs in host defences have been extensively characterised in mammals and rodents, and research on MCs in avian species is emerging. This review surveys the development, morphology and distribution of MCs in different tissues of the poultry and highlight areas that can be exploited for disease control and prevention.

KW - Bacteria

KW - Immune system

KW - Mast cell

KW - Parasite

KW - Poultry

KW - Virus

U2 - 10.1017/S0043933917000526

DO - 10.1017/S0043933917000526

M3 - Review article

AN - SCOPUS:85026734618

VL - 73

SP - 621

EP - 632

JO - World's Poultry Science Journal

JF - World's Poultry Science Journal

SN - 0043-9339

IS - 3

ER -