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Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya: Results from ten-years of the Kenya national school-based deworming programme

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Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya: Results from ten-years of the Kenya national school-based deworming programme. / Okoyo, Collins; Minnery, Mark; Orowe, Idah et al.
In: Heliyon, Vol. 9, No. 10, e20695, 31.10.2023.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Okoyo, C, Minnery, M, Orowe, I, Owaga, C, Campbell, SJ, Wambugu, C, Olick, N, Hagemann, J, Omondi, WP, McCracken, K, Montresor, A, Medley, GF, Fronterre, C, Diggle, P & Mwandawiro, C 2023, 'Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya: Results from ten-years of the Kenya national school-based deworming programme', Heliyon, vol. 9, no. 10, e20695. https://doi.org/10.1016/j.heliyon.2023.e20695

APA

Okoyo, C., Minnery, M., Orowe, I., Owaga, C., Campbell, S. J., Wambugu, C., Olick, N., Hagemann, J., Omondi, W. P., McCracken, K., Montresor, A., Medley, G. F., Fronterre, C., Diggle, P., & Mwandawiro, C. (2023). Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya: Results from ten-years of the Kenya national school-based deworming programme. Heliyon, 9(10), Article e20695. https://doi.org/10.1016/j.heliyon.2023.e20695

Vancouver

Okoyo C, Minnery M, Orowe I, Owaga C, Campbell SJ, Wambugu C et al. Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya: Results from ten-years of the Kenya national school-based deworming programme. Heliyon. 2023 Oct 31;9(10):e20695. Epub 2023 Oct 6. doi: 10.1016/j.heliyon.2023.e20695

Author

Okoyo, Collins ; Minnery, Mark ; Orowe, Idah et al. / Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya : Results from ten-years of the Kenya national school-based deworming programme. In: Heliyon. 2023 ; Vol. 9, No. 10.

Bibtex

@article{abcace4a110b4347baafe78d596fe1de,
title = "Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya: Results from ten-years of the Kenya national school-based deworming programme",
abstract = "Background Kenya is endemic for soil-transmitted helminths (STH) with over 6 million children in 27 counties currently at-risk. A national school-based deworming programme (NSBDP) was launched in 2012 with a goal to eliminate parasitic worms as a public health problem. This study used model-based geostatistical (MBG) approach to design and analyse the impact of the NSBDP and inform treatment strategy changes. Methods A cross-sectional study was used to survey 200 schools across 27 counties in Kenya. The study design, school selection and analysis followed the MBG approach which incorporated historical data on treatment, morbidity and environmental covariates to efficiently predict the helminths prevalence in Kenya. Results Overall, the NSBDP geographic area prevalence for any STH was estimated to sit between 2 % and 0.999. Species-specific thresholds were between 2 % and 0.999. Conclusions Based on the World Health Organization guidelines, STH treatment requirements can now be confidently refined. Ten counties may consider suspending treatment and implement appropriate surveillance system, while another 10 will require treatment once every two years, and the remaining seven will require treatment once every year.",
author = "Collins Okoyo and Mark Minnery and Idah Orowe and Chrispin Owaga and Campbell, {Suzy J.} and Christin Wambugu and Nereah Olick and Jane Hagemann and Omondi, {Wyckliff P.} and Kate McCracken and Antonio Montresor and Medley, {Graham F.} and Claudio Fronterre and Peter Diggle and Charles Mwandawiro",
year = "2023",
month = oct,
day = "31",
doi = "10.1016/j.heliyon.2023.e20695",
language = "English",
volume = "9",
journal = "Heliyon",
issn = "2405-8440",
publisher = "Elsevier",
number = "10",

}

RIS

TY - JOUR

T1 - Model-based geostatistical design and analysis of prevalence for soil-transmitted helminths in Kenya

T2 - Results from ten-years of the Kenya national school-based deworming programme

AU - Okoyo, Collins

AU - Minnery, Mark

AU - Orowe, Idah

AU - Owaga, Chrispin

AU - Campbell, Suzy J.

AU - Wambugu, Christin

AU - Olick, Nereah

AU - Hagemann, Jane

AU - Omondi, Wyckliff P.

AU - McCracken, Kate

AU - Montresor, Antonio

AU - Medley, Graham F.

AU - Fronterre, Claudio

AU - Diggle, Peter

AU - Mwandawiro, Charles

PY - 2023/10/31

Y1 - 2023/10/31

N2 - Background Kenya is endemic for soil-transmitted helminths (STH) with over 6 million children in 27 counties currently at-risk. A national school-based deworming programme (NSBDP) was launched in 2012 with a goal to eliminate parasitic worms as a public health problem. This study used model-based geostatistical (MBG) approach to design and analyse the impact of the NSBDP and inform treatment strategy changes. Methods A cross-sectional study was used to survey 200 schools across 27 counties in Kenya. The study design, school selection and analysis followed the MBG approach which incorporated historical data on treatment, morbidity and environmental covariates to efficiently predict the helminths prevalence in Kenya. Results Overall, the NSBDP geographic area prevalence for any STH was estimated to sit between 2 % and 0.999. Species-specific thresholds were between 2 % and 0.999. Conclusions Based on the World Health Organization guidelines, STH treatment requirements can now be confidently refined. Ten counties may consider suspending treatment and implement appropriate surveillance system, while another 10 will require treatment once every two years, and the remaining seven will require treatment once every year.

AB - Background Kenya is endemic for soil-transmitted helminths (STH) with over 6 million children in 27 counties currently at-risk. A national school-based deworming programme (NSBDP) was launched in 2012 with a goal to eliminate parasitic worms as a public health problem. This study used model-based geostatistical (MBG) approach to design and analyse the impact of the NSBDP and inform treatment strategy changes. Methods A cross-sectional study was used to survey 200 schools across 27 counties in Kenya. The study design, school selection and analysis followed the MBG approach which incorporated historical data on treatment, morbidity and environmental covariates to efficiently predict the helminths prevalence in Kenya. Results Overall, the NSBDP geographic area prevalence for any STH was estimated to sit between 2 % and 0.999. Species-specific thresholds were between 2 % and 0.999. Conclusions Based on the World Health Organization guidelines, STH treatment requirements can now be confidently refined. Ten counties may consider suspending treatment and implement appropriate surveillance system, while another 10 will require treatment once every two years, and the remaining seven will require treatment once every year.

U2 - 10.1016/j.heliyon.2023.e20695

DO - 10.1016/j.heliyon.2023.e20695

M3 - Journal article

VL - 9

JO - Heliyon

JF - Heliyon

SN - 2405-8440

IS - 10

M1 - e20695

ER -