We develop general criteria to construct unified frameworks for inflation and quintessence which employ a unique scalar field to drive both. By using such a minimal theoretical framework we avoid having to fine-tune couplings and mass-scales. In particular the initial conditions for quintessence are already fixed at the end of the inflationary epoch. We provide concrete realizations of the method which meet all inflationary and quintessence requirements, such as the COBE normalization and the resulting spectral index n≈0.97, which is in excellent agreement with the latest cosmic microwave background data.