Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Modelling spatial variation in leukaemia survival data.
AU - Henderson, Robin
AU - Shimakura, S.
AU - Gorst, D.
PY - 2002/12/1
Y1 - 2002/12/1
N2 - In this article we combine ideas from spatial statistics with lifetime data analysis techniques to investigate possible spatial variation in survival of adult acute myeloid leukemia patients in northwest England. Exploratory analysis suggests both clinically and statistically significant variation in survival rates across the region. A multivariate gamma frailty model incorporating spatial dependence is proposed and applied, with results confirming the dependence of hazard on location.
AB - In this article we combine ideas from spatial statistics with lifetime data analysis techniques to investigate possible spatial variation in survival of adult acute myeloid leukemia patients in northwest England. Exploratory analysis suggests both clinically and statistically significant variation in survival rates across the region. A multivariate gamma frailty model incorporating spatial dependence is proposed and applied, with results confirming the dependence of hazard on location.
KW - CANCER
KW - FRAILTY
KW - GEOSTATISTICS
KW - HIERARCHIC MODEL
KW - LATENT PROCESS
KW - SEMIPARAMETRIC MODEL
U2 - 10.1198/016214502388618753
DO - 10.1198/016214502388618753
M3 - Journal article
VL - 97
SP - 965
EP - 972
JO - Journal of the American Statistical Association
JF - Journal of the American Statistical Association
SN - 1537-274X
IS - 460
ER -