Abstract: Spatial resolution of conventional optics, which is necessary for nondestructive trapping of microobjects, is limited by diffraction to a value equal to half of the radiation wavelength. Despite this limitation, use of optical methods is one of the main directions in biological and biomedical researches because only these methods have a minimal impact on living organisms. The rapid advance in this area is largely owing to the development of new optical technologies and the considerable advance in mesoscale photonics, which has allowed researchers to develop techniques for controlling structured beams for optical traps. In this work, we consider some recent trends in the field of optical manipulation based on mesoscale dielectric particles.