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Optimizing Nanohydroxyapatite Nanocomposites for Bone Tissue Engineering

Research output: Contribution to Journal/MagazineJournal articlepeer-review

<mark>Journal publication date</mark>14/01/2020
<mark>Journal</mark>ACS Omega
Issue number1
Number of pages9
Pages (from-to)1-9
Publication StatusPublished
Early online date18/12/19
<mark>Original language</mark>English


Bone tissue engineering involves the combined use of materials with functional properties to regenerate bone. Nanohydroxyapatite (nHA) can influence the behavior of cells. The functional and structural properties of nHA can be controlled during nanoparticle synthesis. This review defines the relationship between the attributes of nHA nanoparticles and their biological effects, focusing on biocompatibility, surface-area-to-volume ratio, bonding chemistry, and substrate functionality. The paper explores how these aspects have been applied in the development of scaffolds for the repair of damaged bone or regeneration of missing bone.