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Oxidative Stress in Poultry: Lessons from the Viral Infections

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Oxidative Stress in Poultry: Lessons from the Viral Infections. / Rehman, Zaib Ur; Meng, Chunchun; Sun, Yingjie et al.
In: Oxidative Medicine and Cellular Longevity, Vol. 2018, 5123147, 10.12.2018.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Rehman, ZU, Meng, C, Sun, Y, Safdar, A, Pasha, RH, Munir, M & Ding, C 2018, 'Oxidative Stress in Poultry: Lessons from the Viral Infections', Oxidative Medicine and Cellular Longevity, vol. 2018, 5123147. https://doi.org/10.1155/2018/5123147

APA

Rehman, Z. U., Meng, C., Sun, Y., Safdar, A., Pasha, R. H., Munir, M., & Ding, C. (2018). Oxidative Stress in Poultry: Lessons from the Viral Infections. Oxidative Medicine and Cellular Longevity, 2018, Article 5123147. https://doi.org/10.1155/2018/5123147

Vancouver

Rehman ZU, Meng C, Sun Y, Safdar A, Pasha RH, Munir M et al. Oxidative Stress in Poultry: Lessons from the Viral Infections. Oxidative Medicine and Cellular Longevity. 2018 Dec 10;2018:5123147. doi: 10.1155/2018/5123147

Author

Rehman, Zaib Ur ; Meng, Chunchun ; Sun, Yingjie et al. / Oxidative Stress in Poultry : Lessons from the Viral Infections. In: Oxidative Medicine and Cellular Longevity. 2018 ; Vol. 2018.

Bibtex

@article{023f6a3c02424c40b19fc92abc275342,
title = "Oxidative Stress in Poultry: Lessons from the Viral Infections",
abstract = "Reactive species (RS), generally known as reactive oxygen species (ROS) and reactive nitrogen species (RNS), are produced during regular metabolism in the host and are required for many cellular processes such as cytokine transcription, immunomodulation, ion transport, and apoptosis. Intriguingly, both RNS and ROS are commonly triggered by the pathogenic viruses and are famous for their dual roles in the clearance of viruses and pathological implications. Uncontrolled production of reactive species results in oxidative stress and causes damage in proteins, lipids, DNA, and cellular structures. In this review, we describe the production of RS, their detoxification by a cellular antioxidant system, and how these RS damage the proteins, lipids, and DNA. Given the widespread importance of RS in avian viral diseases, oxidative stress pathways are of utmost importance for targeted therapeutics. Therefore, a special focus is provided on avian virus-mediated oxidative stresses. Finally, future research perspectives are discussed on the exploitation of these pathways to treat viral diseases of poultry.",
author = "Rehman, {Zaib Ur} and Chunchun Meng and Yingjie Sun and Anum Safdar and Pasha, {Riaz Hussain} and Muhammad Munir and Chan Ding",
year = "2018",
month = dec,
day = "10",
doi = "10.1155/2018/5123147",
language = "English",
volume = "2018",
journal = "Oxidative Medicine and Cellular Longevity",

}

RIS

TY - JOUR

T1 - Oxidative Stress in Poultry

T2 - Lessons from the Viral Infections

AU - Rehman, Zaib Ur

AU - Meng, Chunchun

AU - Sun, Yingjie

AU - Safdar, Anum

AU - Pasha, Riaz Hussain

AU - Munir, Muhammad

AU - Ding, Chan

PY - 2018/12/10

Y1 - 2018/12/10

N2 - Reactive species (RS), generally known as reactive oxygen species (ROS) and reactive nitrogen species (RNS), are produced during regular metabolism in the host and are required for many cellular processes such as cytokine transcription, immunomodulation, ion transport, and apoptosis. Intriguingly, both RNS and ROS are commonly triggered by the pathogenic viruses and are famous for their dual roles in the clearance of viruses and pathological implications. Uncontrolled production of reactive species results in oxidative stress and causes damage in proteins, lipids, DNA, and cellular structures. In this review, we describe the production of RS, their detoxification by a cellular antioxidant system, and how these RS damage the proteins, lipids, and DNA. Given the widespread importance of RS in avian viral diseases, oxidative stress pathways are of utmost importance for targeted therapeutics. Therefore, a special focus is provided on avian virus-mediated oxidative stresses. Finally, future research perspectives are discussed on the exploitation of these pathways to treat viral diseases of poultry.

AB - Reactive species (RS), generally known as reactive oxygen species (ROS) and reactive nitrogen species (RNS), are produced during regular metabolism in the host and are required for many cellular processes such as cytokine transcription, immunomodulation, ion transport, and apoptosis. Intriguingly, both RNS and ROS are commonly triggered by the pathogenic viruses and are famous for their dual roles in the clearance of viruses and pathological implications. Uncontrolled production of reactive species results in oxidative stress and causes damage in proteins, lipids, DNA, and cellular structures. In this review, we describe the production of RS, their detoxification by a cellular antioxidant system, and how these RS damage the proteins, lipids, and DNA. Given the widespread importance of RS in avian viral diseases, oxidative stress pathways are of utmost importance for targeted therapeutics. Therefore, a special focus is provided on avian virus-mediated oxidative stresses. Finally, future research perspectives are discussed on the exploitation of these pathways to treat viral diseases of poultry.

U2 - 10.1155/2018/5123147

DO - 10.1155/2018/5123147

M3 - Journal article

VL - 2018

JO - Oxidative Medicine and Cellular Longevity

JF - Oxidative Medicine and Cellular Longevity

M1 - 5123147

ER -