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Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules: A Direct Suzuki-Miyaura Cross-Coupling on a Thermally Stable CO-RM

Research output: Contribution to Journal/Magazine › Journal article › peer-review

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Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules: A Direct Suzuki-Miyaura Cross-Coupling on a Thermally Stable CO-RM. / Ward, Jonathan S.; Bray, Joshua T. W.; Aucott, Benjamin J. et al.
In: European Journal of Inorganic Chemistry, Vol. 2016, No. 31, 30.11.2016, p. 5044-5051.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Ward, JS, Bray, JTW, Aucott, BJ, Wagner, C, Pridmore, NE, Whitwood, AC, Moir, JWB, Lynam, JM & Fairlamb, IJS 2016, 'Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules: A Direct Suzuki-Miyaura Cross-Coupling on a Thermally Stable CO-RM', European Journal of Inorganic Chemistry, vol. 2016, no. 31, pp. 5044-5051. https://doi.org/10.1002/ejic.201600775

APA

Ward, J. S., Bray, J. T. W., Aucott, B. J., Wagner, C., Pridmore, N. E., Whitwood, A. C., Moir, J. W. B., Lynam, J. M., & Fairlamb, I. J. S. (2016). Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules: A Direct Suzuki-Miyaura Cross-Coupling on a Thermally Stable CO-RM. European Journal of Inorganic Chemistry, 2016(31), 5044-5051. https://doi.org/10.1002/ejic.201600775

Vancouver

Ward JS, Bray JTW, Aucott BJ, Wagner C, Pridmore NE, Whitwood AC et al. Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules: A Direct Suzuki-Miyaura Cross-Coupling on a Thermally Stable CO-RM. European Journal of Inorganic Chemistry. 2016 Nov 30;2016(31):5044-5051. Epub 2016 Oct 5. doi: 10.1002/ejic.201600775

Author

Ward, Jonathan S. ; Bray, Joshua T. W. ; Aucott, Benjamin J. et al. / Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules : A Direct Suzuki-Miyaura Cross-Coupling on a Thermally Stable CO-RM. In: European Journal of Inorganic Chemistry. 2016 ; Vol. 2016, No. 31. pp. 5044-5051.

Bibtex

@article{c96ba8cec5824f7794f71c3ad36d00e9,
title = "Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules: A Direct Suzuki-Miyaura Cross-Coupling on a Thermally Stable CO-RM",
abstract = "A new class of carbon monoxide-releasing molecules (CO-RMs) are reported based on a previously known tetracarbonyl phenylpyridine manganese(I) motif. A pre-functionalized CO-RM undergoes a direct Pd-catalysed Suzuki–Miyaura cross-coupling with phenylboronic acid to give a π-extended three-ring CO-RM. Cross-coupling conditions were modified to allow coupling of a morpholine-containing boronic acid on to a CO-RM, introducing drug-like functionality. An LED system was used to facilitate controlled CO-release. Irradiation using an LED (400 nm or 365 nm) gives rise to faster CO-release, with lower overall input power than traditional use of a TLC lamp (365 nm), as measured by an assay based on the conversion of deoxymyoglobin to carbonmonoxymyoglobin.",
author = "Ward, {Jonathan S.} and Bray, {Joshua T. W.} and Aucott, {Benjamin J.} and Conrad Wagner and Pridmore, {Natalie E.} and Whitwood, {Adrian C.} and Moir, {James W. B.} and Lynam, {Jason M.} and Fairlamb, {Ian J. S.}",
year = "2016",
month = nov,
day = "30",
doi = "10.1002/ejic.201600775",
language = "English",
volume = "2016",
pages = "5044--5051",
journal = "European Journal of Inorganic Chemistry",
issn = "1434-1948",
publisher = "Wiley-VCH Verlag",
number = "31",

}

RIS

TY - JOUR

T1 - Photoactivated Functionizable Tetracarbonyl(phenylpyridine)manganese(I) Complexes as CO-Releasing Molecules

T2 - A Direct Suzuki-Miyaura Cross-Coupling on a Thermally Stable CO-RM

AU - Ward, Jonathan S.

AU - Bray, Joshua T. W.

AU - Aucott, Benjamin J.

AU - Wagner, Conrad

AU - Pridmore, Natalie E.

AU - Whitwood, Adrian C.

AU - Moir, James W. B.

AU - Lynam, Jason M.

AU - Fairlamb, Ian J. S.

PY - 2016/11/30

Y1 - 2016/11/30

N2 - A new class of carbon monoxide-releasing molecules (CO-RMs) are reported based on a previously known tetracarbonyl phenylpyridine manganese(I) motif. A pre-functionalized CO-RM undergoes a direct Pd-catalysed Suzuki–Miyaura cross-coupling with phenylboronic acid to give a π-extended three-ring CO-RM. Cross-coupling conditions were modified to allow coupling of a morpholine-containing boronic acid on to a CO-RM, introducing drug-like functionality. An LED system was used to facilitate controlled CO-release. Irradiation using an LED (400 nm or 365 nm) gives rise to faster CO-release, with lower overall input power than traditional use of a TLC lamp (365 nm), as measured by an assay based on the conversion of deoxymyoglobin to carbonmonoxymyoglobin.

AB - A new class of carbon monoxide-releasing molecules (CO-RMs) are reported based on a previously known tetracarbonyl phenylpyridine manganese(I) motif. A pre-functionalized CO-RM undergoes a direct Pd-catalysed Suzuki–Miyaura cross-coupling with phenylboronic acid to give a π-extended three-ring CO-RM. Cross-coupling conditions were modified to allow coupling of a morpholine-containing boronic acid on to a CO-RM, introducing drug-like functionality. An LED system was used to facilitate controlled CO-release. Irradiation using an LED (400 nm or 365 nm) gives rise to faster CO-release, with lower overall input power than traditional use of a TLC lamp (365 nm), as measured by an assay based on the conversion of deoxymyoglobin to carbonmonoxymyoglobin.

U2 - 10.1002/ejic.201600775

DO - 10.1002/ejic.201600775

M3 - Journal article

VL - 2016

SP - 5044

EP - 5051

JO - European Journal of Inorganic Chemistry

JF - European Journal of Inorganic Chemistry

SN - 1434-1948

IS - 31

ER -