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Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Platinum Catalysed Hydrostannylation of Terminal Alkynes
T2 - Highly Selective Synthesis of Vinyl Stannanes
AU - Roberts, Dean
AU - McLaughlin, Mark
PY - 2023/5/23
Y1 - 2023/5/23
N2 - We present the first study on the application of platinum complexes in the hydrostannylation of terminal alkynes. A range of platinum complexes were screened, with PtCl 2/XPhos proving to provide the best selectivity for the β-(E)-vinyl stannane. The catalyst system is able to provide the corresponding vinyl stannane in selectivities which surpasses that which is typically afforded under palladium catalysis. Additionally, a telescoped hydrometallation/cross-coupling sequence has been developed, allowing for application of the vinyl stannanes without excessive manipulation or purification of the intermediate stannane. (Figure presented.).
AB - We present the first study on the application of platinum complexes in the hydrostannylation of terminal alkynes. A range of platinum complexes were screened, with PtCl 2/XPhos proving to provide the best selectivity for the β-(E)-vinyl stannane. The catalyst system is able to provide the corresponding vinyl stannane in selectivities which surpasses that which is typically afforded under palladium catalysis. Additionally, a telescoped hydrometallation/cross-coupling sequence has been developed, allowing for application of the vinyl stannanes without excessive manipulation or purification of the intermediate stannane. (Figure presented.).
KW - Hydrometallation
KW - Organostannanes
KW - Cross-coupling
KW - Platinum
U2 - 10.1002/adsc.202300379
DO - 10.1002/adsc.202300379
M3 - Journal article
VL - 365
SP - 1602
EP - 1606
JO - Advanced Synthesis & Catalysis
JF - Advanced Synthesis & Catalysis
SN - 1615-4150
IS - 10
ER -