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Point Forces and Their Alternatives in Cell-Based Models for Skin Contraction in Two Dimensions

Research output: Contribution in Book/Report/Proceedings - With ISBN/ISSNConference contribution/Paperpeer-review

Published
Publication date14/01/2020
Host publicationProceedings - 2nd International Conference on Mathematics and Computers in Science and Engineering, MACISE 2020
PublisherIEEE
Pages250-259
Number of pages10
ISBN (electronic)9781728166957
ISBN (print)9781728166957
<mark>Original language</mark>English
Event2020 International Conference on Mathematics and Computers in Science and Engineering (MACISE) - Madrid, Spain
Duration: 14/01/202016/01/2020
https://ieeexplore.ieee.org/xpl/conhome/9186528/proceeding

Conference

Conference2020 International Conference on Mathematics and Computers in Science and Engineering (MACISE)
Country/TerritorySpain
CityMadrid
Period14/01/2016/01/20
Internet address

Publication series

NameProceedings - 2nd International Conference on Mathematics and Computers in Science and Engineering, MACISE 2020

Conference

Conference2020 International Conference on Mathematics and Computers in Science and Engineering (MACISE)
Country/TerritorySpain
CityMadrid
Period14/01/2016/01/20
Internet address

Abstract

Deep tissue injury is often followed by contraction of the scar tissue. This contraction occurs as a result of pulling forces that are exerted by fibroblasts (skin cells). We consider a cell-based approach to simulate the contraction behavior of the skin. Since the cells are much smaller than the wound region, we model cellular forces by means of Dirac Delta distributions. Since Dirac Delta distributions cause a singularity of the solution in terms of loss of smoothness, we study alternative approaches where smoothed forces are considered. We prove convergence and consistency between the various approaches, and we also show computational consistency between the approaches.