Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India

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Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India. / Roychoudhury, P.; Sarma, D. K.; Rajkhowa, S. et al.
In: Transboundary and Emerging Diseases, Vol. 61, No. SUPPL1., 01.01.2014, p. 69-77.

Research output: Contribution to Journal/Magazine › Journal article › peer-review

Harvard

Roychoudhury, P, Sarma, DK, Rajkhowa, S, Munir, M & Kuchipudi, SV 2014, 'Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India', Transboundary and Emerging Diseases, vol. 61, no. SUPPL1., pp. 69-77. https://doi.org/10.1111/tbed.12263

APA

Roychoudhury, P., Sarma, D. K., Rajkhowa, S., Munir, M., & Kuchipudi, S. V. (2014). Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India. Transboundary and Emerging Diseases, 61(SUPPL1.), 69-77. https://doi.org/10.1111/tbed.12263

Vancouver

Roychoudhury P, Sarma DK, Rajkhowa S, Munir M, Kuchipudi SV. Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India. Transboundary and Emerging Diseases. 2014 Jan 1;61(SUPPL1.):69-77. doi: 10.1111/tbed.12263

Author

Roychoudhury, P. ; Sarma, D. K. ; Rajkhowa, S. et al. / Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India. In: Transboundary and Emerging Diseases. 2014 ; Vol. 61, No. SUPPL1. pp. 69-77.

Bibtex

@article{18e77bb1abcf413eaf9e6e3330cff5f6,

title = "Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India",

abstract = "Classical swine fever (CSF) is a highly contagious and the most important disease of pigs worldwide. CSF is enzootic in pig herds in India and continues to cause huge economic losses to pig farmers. Nearly 40% of the total pig population of India is present in the north-eastern (NE) states where pig husbandry plays an important role in the socio-economic development. Pigs reared in the backyards are the only source of livelihood for a majority of poor tribal population in the region. Hardly any CSF vaccination is currently being undertaken in the unorganized pig farming in the NE region due to economic reasons and vaccine unavailability. A thorough understanding of the current epidemiological status of CSF is essential for the effective control of the disease in the NE region. Hence, we carried out molecular characterization of CSFV isolates from field outbreaks during 2011-2012 in the entire north-eastern region of India to establish the genetic groups of prevalent CSF viruses in the region. A total of 17 CSFV isolates obtained from different parts of the NE region were characterized by comparing the sequences of three partial genomic regions of the virus, that is 150nt of 5′ UTR, 190 nt of E2 and 409 nt of NS5B. Of the 17 CSFV isolates, 15 isolates belonged to 1.1 (88.2%) and two isolates (11.8%) belonged to 2.2 subgenogroup. The genogroup 2.2 CSFV were associated with outbreaks in Arunachal Pradesh that shares international borders with Bhutan, Myanmar and China. Genogroup 2.2 CSFV isolated in the present study shared high level of sequence similarity with 2.2 viruses form China, raising the possibility of virus incursion from this region. In summary, we found a continued predominance of 1.1 subgroup and an emergence of 2.2 subgroup CSFV in NE region of India.",

keywords = "Cloning, CSFV, India, Molecular characterization, Sequencing",

author = "P. Roychoudhury and Sarma, {D. K.} and S. Rajkhowa and M. Munir and Kuchipudi, {S. V.}",

year = "2014",

month = jan,

day = "1",

doi = "10.1111/tbed.12263",

language = "English",

volume = "61",

pages = "69--77",

journal = "Transboundary and Emerging Diseases",

issn = "1865-1674",

publisher = "Wiley-Blackwell",

number = "SUPPL1.",

}

RIS

TY - JOUR

T1 - Predominance of genotype 1.1 and emergence of genotype 2.2 classical swine fever viruses in North-Eastern Region of India

AU - Roychoudhury, P.

AU - Sarma, D. K.

AU - Rajkhowa, S.

AU - Munir, M.

AU - Kuchipudi, S. V.

PY - 2014/1/1

Y1 - 2014/1/1

N2 - Classical swine fever (CSF) is a highly contagious and the most important disease of pigs worldwide. CSF is enzootic in pig herds in India and continues to cause huge economic losses to pig farmers. Nearly 40% of the total pig population of India is present in the north-eastern (NE) states where pig husbandry plays an important role in the socio-economic development. Pigs reared in the backyards are the only source of livelihood for a majority of poor tribal population in the region. Hardly any CSF vaccination is currently being undertaken in the unorganized pig farming in the NE region due to economic reasons and vaccine unavailability. A thorough understanding of the current epidemiological status of CSF is essential for the effective control of the disease in the NE region. Hence, we carried out molecular characterization of CSFV isolates from field outbreaks during 2011-2012 in the entire north-eastern region of India to establish the genetic groups of prevalent CSF viruses in the region. A total of 17 CSFV isolates obtained from different parts of the NE region were characterized by comparing the sequences of three partial genomic regions of the virus, that is 150nt of 5′ UTR, 190 nt of E2 and 409 nt of NS5B. Of the 17 CSFV isolates, 15 isolates belonged to 1.1 (88.2%) and two isolates (11.8%) belonged to 2.2 subgenogroup. The genogroup 2.2 CSFV were associated with outbreaks in Arunachal Pradesh that shares international borders with Bhutan, Myanmar and China. Genogroup 2.2 CSFV isolated in the present study shared high level of sequence similarity with 2.2 viruses form China, raising the possibility of virus incursion from this region. In summary, we found a continued predominance of 1.1 subgroup and an emergence of 2.2 subgroup CSFV in NE region of India.

AB - Classical swine fever (CSF) is a highly contagious and the most important disease of pigs worldwide. CSF is enzootic in pig herds in India and continues to cause huge economic losses to pig farmers. Nearly 40% of the total pig population of India is present in the north-eastern (NE) states where pig husbandry plays an important role in the socio-economic development. Pigs reared in the backyards are the only source of livelihood for a majority of poor tribal population in the region. Hardly any CSF vaccination is currently being undertaken in the unorganized pig farming in the NE region due to economic reasons and vaccine unavailability. A thorough understanding of the current epidemiological status of CSF is essential for the effective control of the disease in the NE region. Hence, we carried out molecular characterization of CSFV isolates from field outbreaks during 2011-2012 in the entire north-eastern region of India to establish the genetic groups of prevalent CSF viruses in the region. A total of 17 CSFV isolates obtained from different parts of the NE region were characterized by comparing the sequences of three partial genomic regions of the virus, that is 150nt of 5′ UTR, 190 nt of E2 and 409 nt of NS5B. Of the 17 CSFV isolates, 15 isolates belonged to 1.1 (88.2%) and two isolates (11.8%) belonged to 2.2 subgenogroup. The genogroup 2.2 CSFV were associated with outbreaks in Arunachal Pradesh that shares international borders with Bhutan, Myanmar and China. Genogroup 2.2 CSFV isolated in the present study shared high level of sequence similarity with 2.2 viruses form China, raising the possibility of virus incursion from this region. In summary, we found a continued predominance of 1.1 subgroup and an emergence of 2.2 subgroup CSFV in NE region of India.

KW - Cloning

KW - CSFV

KW - India

KW - Molecular characterization

KW - Sequencing

U2 - 10.1111/tbed.12263

DO - 10.1111/tbed.12263

M3 - Journal article

C2 - 25135466

AN - SCOPUS:84906089573

VL - 61

SP - 69

EP - 77

JO - Transboundary and Emerging Diseases

JF - Transboundary and Emerging Diseases

SN - 1865-1674

IS - SUPPL1.

ER -

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