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Preparation and Synthetic Applications of Phototropone

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Published
<mark>Journal publication date</mark>7/07/2023
<mark>Journal</mark>Journal of Organic Chemistry
Issue number13
Volume88
Number of pages4
Pages (from-to)9514-9517
Publication StatusPublished
Early online date21/06/23
<mark>Original language</mark>English

Abstract

An optimized multigram-scale route to phototropone (bicyclo[3.2.0]hepta-2,6-dien-7-one) is reported via the 4-π-photocyclization of tropone complexed to Lewis acid. Phototropone is a highly versatile molecular building block, and its conversion into 18 novel derivatives using standard transformations is demonstrated, allowing access to a variety of rigid bicyclic scaffolds.