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Reactions to other corticosteroids in patients with allergic contact-dermatitis from hydrocortisone.

Research output: Contribution to Journal/MagazineJournal articlepeer-review

Published
  • S. M. Wilkinson
  • S. Hollis
  • M. H. Beck
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<mark>Journal publication date</mark>1995
<mark>Journal</mark>British Journal of Dermatology
Issue number5
Volume132
Number of pages6
Pages (from-to)766-771
Publication StatusPublished
<mark>Original language</mark>English

Abstract

It has been proposed that corticosteroid cross-reactions occur more frequently within structurally well-defined groups. To test this hypothesis we have compared the patch-test reactions to other corticosteroids in 96 patients allergic to hydrocortisone. We found that our data did not agree with the previously proposed classification. The presence of a substitution at the C6 or C9 position was the most important factor in determining whether a patient would be allergic to another corticosteroid. This information should facilitate the choice of an alternative corticosteroid in patients allergic to hydrocortisone, if facilities for patch testing to other corticosteroids are not available.