Research output: Contribution to Journal/Magazine › Journal article › peer-review
Research output: Contribution to Journal/Magazine › Journal article › peer-review
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TY - JOUR
T1 - Reactions to other corticosteroids in patients with allergic contact-dermatitis from hydrocortisone.
AU - Wilkinson, S. M.
AU - Hollis, S.
AU - Beck, M. H.
PY - 1995
Y1 - 1995
N2 - It has been proposed that corticosteroid cross-reactions occur more frequently within structurally well-defined groups. To test this hypothesis we have compared the patch-test reactions to other corticosteroids in 96 patients allergic to hydrocortisone. We found that our data did not agree with the previously proposed classification. The presence of a substitution at the C6 or C9 position was the most important factor in determining whether a patient would be allergic to another corticosteroid. This information should facilitate the choice of an alternative corticosteroid in patients allergic to hydrocortisone, if facilities for patch testing to other corticosteroids are not available.
AB - It has been proposed that corticosteroid cross-reactions occur more frequently within structurally well-defined groups. To test this hypothesis we have compared the patch-test reactions to other corticosteroids in 96 patients allergic to hydrocortisone. We found that our data did not agree with the previously proposed classification. The presence of a substitution at the C6 or C9 position was the most important factor in determining whether a patient would be allergic to another corticosteroid. This information should facilitate the choice of an alternative corticosteroid in patients allergic to hydrocortisone, if facilities for patch testing to other corticosteroids are not available.
U2 - 10.1111/j.1365-2133.1995.tb00724.x
DO - 10.1111/j.1365-2133.1995.tb00724.x
M3 - Journal article
VL - 132
SP - 766
EP - 771
JO - British Journal of Dermatology
JF - British Journal of Dermatology
SN - 1365-2133
IS - 5
ER -